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Main description:
Cancer Genomics and Proteomics: Methods and Protocols, Second Edition includes methods for the analyses of cancer genome and proteome that have illuminated us about the changes in cancer cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Cancer Genomics and Proteomics: Methods and Protocols, Second Edition seeks to aid scientists in the further study into various aspects of tumor initiation and progression.
Contents:
1. Genome-Wide Mapping Of RNA Pol-II Promoter Usage In Mouse Tissues By Chip-Seq
Sharmistha Pal, Ravi Gupta And Ramana V. Davuluri
2. Using Native Chromatin Immunoprecipitation To Interrogate Histone Variant Protein Deposition In Embryonic Stem Cells
Zito Tseng, Tao Wu, Yifei Liu, Mei Zhong, And Andrew Xiao
3. Reduced Representation Bisulfite Sequencing To Identify Global Alteration In The DNA Methylation
Arvindhan Nagarajan, Christine Roden And Narendra Wajapeyee
4. A High-Throughput Microrna Expression Profiling System
Yanwen Guo, Stephen Mastriano And Jun Lu
5. Using Pooled Mir30-Shrna Library For Cancer Lethal And Synthetic Lethal Screens
Liam Changwoo Lee, Shaojian Gao, Qiuning Li, And Ji Luo
6. Genome-Wide RNA Interference Screening To Identify Regulators Of Epigenetic Silencing Of A Tumor Suppressor Gene
Matteo Forloni, Thuy Ho And Narendra Wajapeyee
7. A Diphtheria Toxin Negative Selection In RNA Interference Screening
Zhi Sheng, Susan F Murphy, Sujuan Guo And Michael R Green
8. Cancer Metabolism: Crosstalk Between Signaling And O-Glcnacylation
Christina M. Ferrer And Mauricio J. Reginato
9. Targeted Genome Modification Via Triple Helix Formation
Adele S. Ricciardi, Nicole A. Mcneer, Kavitha K. Anandalingam, W. Mark Saltzman, Peter M. Glazer
10. Synthesis Of Stabilized Alpha-Helical Peptides
Federico Bernal And Samuel G. Katz
11. Arginine-Grafted Biodegradable Polymer: A Versatile Transfection Reagent For Both DNA And Sirna
Jagadish Beloor, Hye Yeong Nam, Sang-Kyung Lee And Priti Kumar
12. Using Laco Arrays To Monitor DNA Double-Strand Break Dynamics In Live Schizosaccharomyces Pombe Cells
Bryan A. Leland And Megan C. King
13. Zebrafish As A Platform To Study Tumor Progression
Corrie A. Painter And Craig J. Ceol
14. Clonal Screens To Find Modifiers Of Partially Penetrant Phenotypes In C. Elegans
Michael E. Hurwitz
15. Serum Profiling Using Protein Microarrays To Identify Disease Related Antigens.
Donald Sharon And Michael Snyder
16. Interrogation Of In Vivo Protein-Protein Interactions Using Transgenic Mouse Models And Stable Isotope Labeling
Anwesha Dey, Jiansheng Wu, Donald S. Kirkpatrick
17. New Biophysical Methods To Study The Membrane Activity Of Bcl-2 Proteins
Stephanie Bleicken And Ana J. Garcia-Saez
18. Purification Of Recombinant 2XMBP Tagged Human Proteins From Human Cells
Ryan Jensen
19. Computational Analysis In Cancer Exome Sequencing
Perry Evans, Yong Kong, And Michael Krauthammer
20. Matrix Factorization Methods For Integrative Cancer Genomics
Shihua Zhang And Xianghong Jasmine Zhou
21. Computational Methods For DNA Copy-Number Analysis Of Tumors
Jude Kendall And Alexander Krasnitz
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: July, 2014
Pages: 250
Weight: 7281g
Availability: Available
Subcategories: Genetics, Oncology
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