(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease. The second edition of Autoimmunity: Methods and Protocols researchers in the field detail many of the most up-to-date methods which are now commonly used to study autoimmunity. The first half the book focuses on methods and protocols used to assess immunological and biochemical pathways of diseases pathogenesis in human subjects. While the second half investigates treatment of inflammatory arthritis, experimental allergic encephalomyelitis (EAE), IDDM, scleroderma, and uveitis in animal models and assessment of genetic, immunological, and biochemical parameters underlying spontaneous or exogenous antigen-induced diseases. Written in the highly successful Methods in Molecular Biology(tm) series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.
Through and intuitive, Autoimmunity: Methods and Protocols, Second Edition seeks to aid scientists in the autoimmunity field to extract new meaning of old models and developing new ones.
Contents:
1. Pathogenesis and Spectrum of Autoimmunity
Andras Perl
2. Mapping Susceptibility Gene in Systemic Lupus Erythematosus
R. Hal Scofield and Kenneth M. Kaufman
3. Methods and Protocols to study T Cell Signaling Abnormalities in Human Systemic Lupus Erythematosus
Vaishali R. Moulton, Mindy S. Lo, and George C. Tsokos
4. Assessment of Mitochondrial Dysfunction in Lymphocytes of Patients with Systemic Lupus Erythematosus
Andras Perl, Robert Hanczko, and Edward Doherty
5. The Role of Endocytic Recycling in Autoimmunity
Tiffany Telarico, Andras Perl
6. Multi-Parameter Flow Cytometry and Bioanalytics for B Cell Profiling in Systemic Lupus Erythematosus
Denise A. Kaminski, Chungwen Wei, Alexander Rosenberg, F. Eun-Hung Lee, and Ignacio Sanz
7. Experimental Use of Mouse Models of Systemic Lupus Erythermatosus
Standford L. Peng
8. Murine Models of Lupus Induced By Hypomethlated T Cell
(DNA hypomethylation and lupus....)
Bruce Richardson, Amr H Sawalha, Donna Ray and Raymond Yung
9. Aspects of CNS Lupus: Mouse Models of Anti-NMDA Receptor Antibody Mediated Reactivity
Czeslawa Kowal and Betty Diamond
10. Analysis of Renal Mononuclear Phagocytes in Murine Models of SLE
Ramalingam Bethunaickan, Ranjit Sahu and Anne Davidson
11. A Murine Autoimmune Model of Rheumatoid Arthritis and Systemic Lupus Erythematosus Associated with Deregulated Production of IL-17 and IL-21
Partha S. Biswas, Kyuho Kang, Sanjay Gupta, Govind Bhagat, and Alessandra B. Pernis
12. The Parent-into-F1 Murine Model in the Study of Lupus-like Autoimmunity and CD8 Cytotoxic T Lymphocyte Function
Kateryna Soloviova, Maksym Puliaiev, Anthony Foster, Charles S. Via
13. Genetic Approach to Study Lupus Glomerulonephritis Yan Ge, Michael G. Brown, Hongyang Wang, PhD and Shu Man Fu
14. Animal Models of Primary Biliary Cirrhosis: Materials and Methods
Patrick S.C. Leung, Guo Xiang Yang, Amy Dhirapong, Koichi Tsuneyama, William M. Ridgway, and M. Eric Gershwin
15. Modeling Innate Immunity in Murine Skin: Utilization of Subcutaneous Osmotic Pumps for Inflammatory and Fibrotic Skin Disease
Michael Dimarzio, Giuseppina Farina, Robert Lafyatis
16. Flow Cytometric Identification of Fibrocytes in Scleroderma Lung Disease
Thomas M. Russell, Erica L. Herzog, Richard Bucala
17. Oxidative Stress and Beta Cell Dysfunction
Yaima L. Lightfoot, Jing Chen, Clayton E. Mathews
18. Experimental Autoimmune Encephalomyelitis
Praveen Rao, Ph.D and Benjamin M. Segal
19. Mouse Models of Multiple Sclerosis: Experimental Autoimmune Encephalomyelitis and Theiler's Virus-Induced Demyelinating Disease Derrick P. McCarthy, Maureen H. Richards, and Stephen D. Miller
20. Pathorgenesis of Multiple Sclerosis What Can we Learn from the Cuprizone Model
Peter Acs, Bernadette Kalman
21. Assessing Inflammatory Disease at Mucosal Surfaces in Murine Genetic Models
Engelman, R.W., and Kerr, W.G.
22. Rodent Models of Experimental Autoimmune Uveitis (EAU)
Rajeev K. Agarwal, Phyllis B. Silver and Rachel R. Caspi
23. Tolerance Induction via B-cell Delivered Gene Therapy
Robert J. Rossi, Belinda M. Jackson, Ai-Hong Zhang, and David W. Scott
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: August, 2012
Pages: 500
Weight: 1164g
Availability: Available
Subcategories: Genetics, Immunology
From the same series
