(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
In Quantitative Trait Loci: Methods and Protocols, a panel of highly experienced statistical geneticists demonstrate in a step-by-step fashion how to successfully analyze quantitative trait data using a variety of methods and software for the detection and fine mapping of quantitative trait loci (QTL). Writing for the nonmathematician, these experts guide the investigator from the design stage of a project onwards, providing detailed explanations of how best to proceed with each specific analysis, to find and use appropriate software, and to interpret results. Worked examples, citations to key papers, and variations in method ease the way to understanding and successful studies. Among the cutting-edge techniques presented are QTDT methods, variance components methods, and the Markov Chain Monte Carlo method for joint linkage and segregation analysis.
Contents:
Part I. Mapping Quantitative Trait Loci in Humans
Association Studies
Jennifer H. Barrett
Parametric Linkage Analysis
Lyle J. Palmer, Audrey H. Schnell, John S. Witte, and Robert C. Elston
Nonparametric Linkage Analysis: I. Haseman-Elston
Chad P. Garner
Nonparametric Linkage Analysis: II. Variance Components
Angela J. Marlow
Linkage and Association: The Transmission/Disequilibrium Test for QTLs
Mark M. Iles
Joint Linkage and Segregation Analysis Using Markov Chain Monte Carlo Methods
Ellen M. Wijsman
Part II. Mapping Quantitative Trait Loci in Rodents
Approaches to the Analysis of QTL Data in Mice, Using the Nonobese Diabetic Mouse as an Example
Heather J. Cordell
Experimental Designs for QTL Fine Mapping in Rodents
Anne Shalom and Ariel Darvasi
Approaches to the Analysis of Complex Quantitative Phenotypes and Marker Map Construction Based on the Analysis of Rat Models of Hypertension
Dominique Gauguier and Nilesh Samani
A Case Study of QTL Analysis in a Mouse Model of Asthma
Youming Zhang and William Cookson
Part III. Mapping Quantitative Trait Loci in Agricultural Settings
QTL Analysis in Plants
Shizhong Xu
QTL Analysis in Livestock
Joao L. Rocha, Daniel Pomp, and L. Dale Van Vleck
Index
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2010
Pages: 372
Weight: 546g
Availability: Available
Subcategories: Genetics
From the same series
