(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
Cardiovascular disease is the leading cause of death in developed countries, but is quickly becoming an epidemic in such well-populated countries as China, India, and other developing nations. Cardiovascular research is the key to the prevention, diagnosis, and management of cardiovascular disease. Vigorous and cross-disciplinary approaches are required for successful card- vascular research. As the boundaries between different scientific disciplines, particularly in the life sciences, are weakening and disappearing, a successful investigator needs to be competent in many different areas, including genetics, cell biology, biochemistry, physiology, and structural biology. The newly developed field of molecular medicine is a cross-disciplinary science that seeks to comprehend disease causes and mechanisms at the molecular level, and to apply this basic research to the prevention, diagnosis, and treatment of diseases and disorders. This volume in the Methods in Molecular Medicine series, C- diovascular Disease, provides comprehensive coverage of both basic and the most advanced approaches to the study and characterization of cardiovascular disease. These methods will advance knowledge of the mechanisms, diagnoses, and treatments of cardiovascular disease. Cardiovascular Disease is a timely volume in which the theory and pr- ciples of each method are described in the Introduction section, followed by a detailed description of the materials and equipment needed, and step-by-step protocols for successful execution of the method. A notes section provides advice for potential problems, any modifications, and alternative methods.
Contents:
Cytogenetic Analysis of Cardiovascular Disease.- Fluorescence In Situ Hybridization in Cardiovascular Disease.- Comparative Genomic Hybridization by Microarray for the Detection of Cytogenetic Imbalance.- Construction of Somatic Cell Hybrid Lines.- LINKAGE Programs.- SAGE Programs.- Linkage Analysis for Complex Diseases Using Variance Component Analysis.- Genome Resources and Comparative Analysis Tools for Cardiovascular Research.- Positional Cloning.- Positional Cloning.- Chromosome Substitution Strains.- Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms Conferring Risk of Myocardial Infarction.- Mutation Detection in Congenital Long QT Syndrome.- High-Throughput Single-Nucleotide Polymorphisms Genotyping.- Genotyping Single-Nucleotide Polymorphisms by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight-Based Mini-Sequencing.
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: September, 2006
Pages: 250
Weight: 508g
Availability: Available
Subcategories: Cardiovascular Medicine
From the same series
Pottumarthi V Prasad
Michael J. Soares
Mary Kearns-Jonker
Michael J. Soares
John M. S. Bartlett
Guy B. Faguet
Douglas B. Lowrie
Johnson Y. N. Lau
Barbara Driscoll
Stephen M. Palfrey
Alex A. Adjei
Barbara Driscoll
Andrew J. Pollard
Paul Jackson
G. E. Francis
Nagy A. Habib
Marion Leboyer
David J. Perry
Nicholas J. Goulden
Duncan F. Rogers
Hansjorg Hauser
Nair Sreejayan
Jacqueline Boultwood
Brian J. Nickoloff
Donna H. Wang
William R. Skach
Derek Kinchington
John Sinclair
M.Maral Mouradian
P. Elizabeth Rakoczy
Susan A. Brooks
Ronald J.A. Trent
Jerome P. Fennell
Rosalyn D. Blumenthal
Frederic De Ceuninck
Alan Thornhill
Jochen Decker
Erika J. Ernst
Angelo Corti
Andrew P. Cope
Qing Wang
Qing Wang
Jun Zhou
Joseph E. Roulston
Simon J. Read
Frederic De Ceuninck
Margaret H. Baron
Meral Beksac
Andrew Robinson
John Varga
Sabire Ozcan
Tim Illidge
Clare Davy
Emmanuel S. Onaivi
Mark W. Saltzman
William S.M. Wold
W. Scott Champney
William S.M. Wold
Michael S. Goligorsky
Andrew P. Cope
Zhongjie Sun
Rosalyn D. Blumenthal
Ross D. Brown
Daniel J. J. Carr
Thomas O. Joos
Gloria H. Su
Andrew J. Pollard
John R. Stephenson
P. Frederick Sparling
Yvonne A. Barnett
Andrew J.T. George
Tanya Parish
Derek T. O'Hagan
Mark A. Herbert
Ronald L. Nagel
Rob Elles
Margaret Hanausek
C.L. Clayton
Denise L. Doolan
Luisa A. DiPietro
Caroline J. Springer
Harry F. Baker
Stuart H. Ralston
Sukriti Nag
Wieslaw M. Kazmierski
Jonathan M. Rhodes
Robert Brown
Udo Schumacher
Hugh A. Tilson
Udo Schumacher
Burkhard Ludewig
Thomas J. Evans
Nigel M. Hooper
Angela F. Drew
Jack H. Mydlo
Katherine Bushby
John Q. Wang
Zhizhong Z. Pan
Steven M. Powell
Kian Fan Chung
Anthony A. Killeen
Andrew H. Baker
James Gray
Luke A.J. O'Neill
Curtis A. Machida
Robert K. Hamatake
Meinir G. Jones
Nair Sreejayan
Meinir G. Jones
W. Scott Champney
Ronald J.A. Trent
Jun Zhou
Hansjorg Hauser
Andrew P. Cope
Andrew P. Cope
Alan R. Thornhill
Meral Beksac
Ann E. Tollefson
Ann E. Tollefson
Qing Wang
Mark W. Saltzman
Mary Kearns-Jonker