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Transforming Growth Factor-Beta in Cancer Therapy, Volume II
Cancer Treatment and Therapy
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Main description:

Transforming Growth Factor- ss in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ss (TGF- ss) in cancer treatment and therapy. The second volume, Cancer Treatment in Therapy, is divided into three parts.

The companion volume details the role of TGF- ss on basic and clinical biology.


Contents:

Transforming Growth Factor-ss in Cancer Therapy
Volume 2: Cancer Treatment and Therapy
Sonia B. Jakowlew, Ph.D., Editor
The Humana Press, Inc., Publisher
TABLE OF CONTENTS

In Memorium for Anita B. Roberts, PhD
John M. McPherson*

Preface
Sonia B. Jakowlew*

Foreward
Carl-Henrick Heldin*

Contributors

Part I. Transforming Growth Factor-ss in Developing and Advanced Cancers

1 Transforming Growth Factor-ss Signaling in Pancreas Development and
Pancreatic Cancer
Sushil Rane*, Huei-Min Lin, Ji-Hyeon Lee, and Wan Jiao

2 Role of Transforming Growth Factor-ss (TGF-ss) in the Pathogenesis of
Head and Neck Squamous Cell
Carcinoma (HNSCC)
Stephen M. Weber, Shi-Long Lu, Sophia Bernstein, and Xiao-Jing Wang*

3 TGF-ss, Smads and Cervical Cancer
Devarajan Karunagaran* and Goodwin Jinesh

4 TGF-ss Signaling and Biglycan in Pancreatic Cancer
Hendrik Ungefroren*

5 TGF-ss Signaling in Endometrial Cancer
Dagmara Piestrzeniewicz-Ulanska*, David H. McGuinnes, and Grant R.
Yeaman

6 TGF-ss Ligands, TGF-AY Receptors, and Lung Cancer
Guiying Wang, Rongmei Zhang, Xiaohua Hu, Jiucun Wang, Lindsey J. Leach,
and Zewei Luo*

7 Role of TGF-ss in Osteolytic Bone Metastases
Laurent Bartholin* and Thesesa A. Guise

8 Hormonal Regulation of Transforming Growth Factor-beta in Breast
Cancer
Miriam Buck* and Cornelius Knabbe

9 TGF-ss Signaling in Esophageal Cancer
Minoru Fukuchi*, Hiroyuki Kato, and Hiroyuki Kuwano

10 TGF-beta and HER2/ErbB2 and Breast Cancer Progression
Natasa Todorovic-Rakovic*

11 TGF-beta dependent T Cell Regulation in Colitis and Colon Cancer
Christoph Becker* and Markus F. Neurath

12 Role of Transforming Growth Factor-beta in the Kidney - Physiology
and Pathology
Elena Gagliardini and Ariela Benigni*

13 Perturbations of TGF-ss Signaling in Leukocytes as Driversof
Leukemogenesis and Epithelial
Tumorigenesis
Lawrence A. Wolfraim* and John J. Letterio

14 Transforming Growth Factor-ss in Brain Functions and Dysfunctions
Denis Vivien*, Karim Benchenane, and Carine Ali

15 Inhibition of TGF-ss Signaling in Multiple Myeloma and it's Bone
Marrow Environment
Hiroshi Yasui, Teru Hideshima, and Kenneth C. Anderson*

16 Key Roles of Smad3 in TGF-ss Responses in the Prostate
Kyung Song and David Danielpour*

17 Smad Signaling in Leukemic Growth and Differentiation: Crosstalk
Between Smad and Multiple
Pathways Through Activation of the TGF-ss Type I Receptor
Francis W. Ruscetti*, Salem Akel, Maria Birchenall-Roberts, Zhouhong
Cao, and Anita Roberts

Part II. Transforming Growth Factor-ss in Cancer Treatment and Therapy

18 High Throughput Screening of Protein Interaction Networks in the
TGFss Interactome: Understanding the
Signaling Mechanisms Driving Tumor Progression
Miriam Barrios-Rodiles, Alicia Viloria-Petit, Kevin R. Brown, Igor
Jurisica, and Jeffrey L.
Wrana*

19 Tumor Suppressor and Pro-Progression Roles for TGF-ss in Breast Cancer
Ethan Kohn* and Binwu Tang

20 Tumor Suppressors p53 and TGF-ss Converge to Regulate the
Alpha-fetoprotein - Oncodevelopmental
Tumor Marker
Deepti S. Wilkinson and Michelle Craig Barton*

21 TGF-ss1: Roles in DNA Damage Responses
Kumari L. Andarawewa, Julie Kirshner, Joni D. Mott, and Mary Helen
Barcellos-Hoff*

22 The Rationale For and Effects of Targeting TGF-beta for Glioma
Therapy
Anita B. Hjelmeland* and Jeremy N. Rich

23 Tumor Suppressor Function of TGF-ss1 in T Cells
Ramireddy Bommireddy* and Thomas Doetschman

24 Therapeutic Effects of Adenovirus-mediated Gene Transfer of TGF-ss Signal Antagonists on Undesirable
Epithelial-mesenchymal Transition and Neovascularization
Shizuka Saika*

25 Role of TGF-ss in Tumor Protection


PRODUCT DETAILS

ISBN-13: 9781617377365
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2010
Pages: 814
Weight: 1517g
Availability: Available
Subcategories: Oncology, Pathology
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