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Main description:
Transforming Growth Factor- ss in Cancer Therapy, Vols. 1 and 2, provides a compendium of findings about the role of transforming growth factor- ss (TGF- ss) in cancer treatment and therapy. The second volume, Cancer Treatment in Therapy, is divided into three parts.
The companion volume details the role of TGF- ss on basic and clinical biology.
Contents:
Transforming Growth Factor-ss in Cancer Therapy
Volume 2: Cancer Treatment and Therapy
Sonia B. Jakowlew, Ph.D., Editor
The Humana Press, Inc., Publisher
TABLE OF CONTENTS
In Memorium for Anita B. Roberts, PhD
John M. McPherson*
Preface
Sonia B. Jakowlew*
Foreward
Carl-Henrick Heldin*
Contributors
Part I. Transforming Growth Factor-ss in Developing and Advanced Cancers
1 Transforming Growth Factor-ss Signaling in Pancreas Development and
Pancreatic Cancer
Sushil Rane*, Huei-Min Lin, Ji-Hyeon Lee, and Wan Jiao
2 Role of Transforming Growth Factor-ss (TGF-ss) in the Pathogenesis of
Head and Neck Squamous Cell
Carcinoma (HNSCC)
Stephen M. Weber, Shi-Long Lu, Sophia Bernstein, and Xiao-Jing Wang*
3 TGF-ss, Smads and Cervical Cancer
Devarajan Karunagaran* and Goodwin Jinesh
4 TGF-ss Signaling and Biglycan in Pancreatic Cancer
Hendrik Ungefroren*
5 TGF-ss Signaling in Endometrial Cancer
Dagmara Piestrzeniewicz-Ulanska*, David H. McGuinnes, and Grant R.
Yeaman
6 TGF-ss Ligands, TGF-AY Receptors, and Lung Cancer
Guiying Wang, Rongmei Zhang, Xiaohua Hu, Jiucun Wang, Lindsey J. Leach,
and Zewei Luo*
7 Role of TGF-ss in Osteolytic Bone Metastases
Laurent Bartholin* and Thesesa A. Guise
8 Hormonal Regulation of Transforming Growth Factor-beta in Breast
Cancer
Miriam Buck* and Cornelius Knabbe
9 TGF-ss Signaling in Esophageal Cancer
Minoru Fukuchi*, Hiroyuki Kato, and Hiroyuki Kuwano
10 TGF-beta and HER2/ErbB2 and Breast Cancer Progression
Natasa Todorovic-Rakovic*
11 TGF-beta dependent T Cell Regulation in Colitis and Colon Cancer
Christoph Becker* and Markus F. Neurath
12 Role of Transforming Growth Factor-beta in the Kidney - Physiology
and Pathology
Elena Gagliardini and Ariela Benigni*
13 Perturbations of TGF-ss Signaling in Leukocytes as Driversof
Leukemogenesis and Epithelial
Tumorigenesis
Lawrence A. Wolfraim* and John J. Letterio
14 Transforming Growth Factor-ss in Brain Functions and Dysfunctions
Denis Vivien*, Karim Benchenane, and Carine Ali
15 Inhibition of TGF-ss Signaling in Multiple Myeloma and it's Bone
Marrow Environment
Hiroshi Yasui, Teru Hideshima, and Kenneth C. Anderson*
16 Key Roles of Smad3 in TGF-ss Responses in the Prostate
Kyung Song and David Danielpour*
17 Smad Signaling in Leukemic Growth and Differentiation: Crosstalk
Between Smad and Multiple
Pathways Through Activation of the TGF-ss Type I Receptor
Francis W. Ruscetti*, Salem Akel, Maria Birchenall-Roberts, Zhouhong
Cao, and Anita Roberts
Part II. Transforming Growth Factor-ss in Cancer Treatment and Therapy
18 High Throughput Screening of Protein Interaction Networks in the
TGFss Interactome: Understanding the
Signaling Mechanisms Driving Tumor Progression
Miriam Barrios-Rodiles, Alicia Viloria-Petit, Kevin R. Brown, Igor
Jurisica, and Jeffrey L.
Wrana*
19 Tumor Suppressor and Pro-Progression Roles for TGF-ss in Breast Cancer
Ethan Kohn* and Binwu Tang
20 Tumor Suppressors p53 and TGF-ss Converge to Regulate the
Alpha-fetoprotein - Oncodevelopmental
Tumor Marker
Deepti S. Wilkinson and Michelle Craig Barton*
21 TGF-ss1: Roles in DNA Damage Responses
Kumari L. Andarawewa, Julie Kirshner, Joni D. Mott, and Mary Helen
Barcellos-Hoff*
22 The Rationale For and Effects of Targeting TGF-beta for Glioma
Therapy
Anita B. Hjelmeland* and Jeremy N. Rich
23 Tumor Suppressor Function of TGF-ss1 in T Cells
Ramireddy Bommireddy* and Thomas Doetschman
24 Therapeutic Effects of Adenovirus-mediated Gene Transfer of TGF-ss Signal Antagonists on Undesirable
Epithelial-mesenchymal Transition and Neovascularization
Shizuka Saika*
25 Role of TGF-ss in Tumor Protection
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2010
Pages: 814
Weight: 1517g
Availability: Available
Subcategories: Oncology, Pathology
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