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Insulin-like Growth Factors and Cancer
From Basic Biology to Therapeutics
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€219.59
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€219.59
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MORE ABOUT THIS BOOK

Main description:

The book will detail the history, successes, and failures of targeted therapies for cancer, with a particular focus on IGF systems and cancer.


Contents:

Preface.- Epidemiology of IGF-1 and Cancer.- Aging and Cancer: The IGF-I Connection.- Obesity, Type 2 Diabetes and Cancer.- IGF System and Breast Cancer.- The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression.- Mouse Models of IGF-1 Deficiency.- Insulin-like Growth Factor Signaling in Pediatric Sarcomas.- Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer.- Mouse Models of IGF-1R and Cancer.- Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy.- Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer.- Calories and Cancer: The Role of Insulin-like Growth Factor.- Cancer Cell Metabolism.- Overlaps between the Insulin and IGF-1R and Cancer.- Index


PRODUCT DETAILS

ISBN-13: 9781461429623
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: October, 2013
Pages: 296
Weight: 456g
Availability: Available
Subcategories: Oncology, Pharmacology
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