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Main description:
A practical guide to the design, conduction, analysis and reporting of clinical trials with anticancer drugs.
Contents:
Section 1:
Chapter 1: Basic Biostatistics for the Clinical Trialist
Authors: Elizabeth G. Hill and Elizabeth Garrett-Mayer
Chapter 2: Fundamental Concepts in Clinical Pharmacology
Authors: Daniel L. Gustafson and Erica L. Bradshaw-Pierce
Chapter 3: Bioanalytical Methods in Clinical Drug Development
Authors: Walter J. Loos, Peter de Bruijn, Alex Sparreboom
Section 2
Chapter 1: Preclinical Models for Anticancer Drug Development
Author: Edward Sausville
Section 3
Chapter 1: Phase I Clinical Trials with Anticancer Agents
Authors: Stephen Leong, Justin Call, Alex Adjei, Wells Messersmith
Chapter 2: Phase II Clinical Trials with Anticancer Agents
Authors: Hui Gan, J. Jack Lee, Lillian L. Siu
Chapter 3: Phase III Clinical Trials with Anticancer Agents
Authors: Wendy Parulekar and Daniel J. Sargent
Chapter 4: Pharmacokinetic Studies in Early Anticancer Drug Development
Authors: Sharyn D Baker and Alex Sparreboom
Chapter 5: Pharmacodynamic Studies in Early Phase Drug Development
Authors: D. Ross Camidge, Robert C. Doebele and Antonio Jimeno
Chapter 6: Prediction of Antitumor response
Authors: Yu Shyr and Fred R. Hirsch
Chapter 7: Imaging Studies in Anticancer Drug Development
Author: David Mankoff
Section 4
Chapter 1: Role of the US Food and Drug Administration in Cancer Drug Development
Authors: Ann T. Farrell, Ramzi N. Dagher and Richard Pazdur
Section 5
Chapter 1: Early Clinical Trials with Cytotoxic Agents
Authors: M.J.A. de Jonge and Jaap Verweij
Chapter 2: Challenges and Sucesses in Developing Effective Anti-Angiogenic Agents
Authors: Laura QM Chow and S Gail Eckhardt
Chapter 3: Targeted Therapeutics in Cancer Treatment
Authors: Colin D. Weekes and Manuel Hidalgo
Chapter 4: Cancer Chemoprevention
Authors: Christopher H. Lieu, William N. William Jr., Scott M. Lippman
Chapter 5: Combined Modality Therapy in Cancer Management
Authors: David Raben and Kyle Rusthoven
Chapter 6: Cancer Vaccines
Author: Dan Laheru
Chapter 7: Optimizing the Development of Antibodies as Treatment for Cancer
Authors: Craig P Carden, Hendrik-Tobias Arkenau and JS de Bono
Chapter 8: Oligonucleotide Therapeutics
Authors: Cy A Stein, Britta Hoehn, John Rossi
Chapter 9: Anticancer Drug Development in Pediatric Patients
Authors: Lia Gore and Margaret Macy
Chapter 10: Clinical Trials in Special Populations
Authors: S. Percy Ivy, MD; Merrill J. Egorin, MD; Chris H. Takimoto, MD, PhD; and Jeannette Y. Wick, RPh
Section 6:
Chapter 1. NCI Sponsored Clinical Trials
Author: Janet E. Dancey and Andriana Papaconstantinou
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: December, 2010
Pages: 692
Weight: 1196g
Availability: Available
Subcategories: Oncology
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