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Main description:
Divided into two convenient sections, Protein Kinase Technologies collects contributions from experts in the field examining recent methodologies and techniques generally applicable to protein kinase research as well as to individual protein kinases which require special attention in neuroscience. These chapters will not only be practical instructions useful for readers' daily work in setting up and performing research but also thought-provoking and enjoyable reviews of recent advancements of individual protein kinases in neuroscience. Written for the highly successful Neuromethods series, this work contains the kind of detailed description and implementation advice that is crucial for getting optimal results.
Authoritative and accessible, Protein Kinase Technologies seeks to foster cross-talk among investigators who study different protein kinases, and will also be beneficial for the entry of new investigators into this pivotal field.
Contents:
Part I: Recent General Methodologies
1. Visualization of Protein Kinase Activities in Living Cells
Kazuhiro Aoki, Naoki Komatsu, Akihiro Goto, and Michiyuki Matsuda
2. Phos-Tag Affinity Electrophoresis for Protein Kinase Profiling
Eiji Kinoshita, Emiko Kinoshita-Kikuta, and Tohru Koike
3. Large-Scale Protein Phosphorylation Analysis by Mass Spectrometry-Based Phosphoproteomics
Wei-Chi Ku, Naoyuki Sugiyama, and Yasushi Ishihama
Part II: Individual Protein Kinases
4. Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)
Steven J. Coultrap and K. Ulrich Bayer
5. CASK: A Specialized Neuronal Kinase
15. Diacylglycerol Kinase (DGK)
Konark Mukherjee
6. Cyclin-Dependent Kinase 5 (Cdk5): Preparation and Measurement of Kinase Activity
15. Diacylglycerol Kinase (DGK)
Seiji Minegishi and Shin-ichi Hisanaga
7. ErbB Membrane Tyrosine Kinase Receptors: Analyzing Migration in a Highly Complex Signaling System
15. Diacylglycerol Kinase (DGK)
Nicole M. Brossier, Stephanie J. Byer, Lafe T. Peavler, and Steven L. Carroll
8. The Extracellular-Signal Regulated Kinase (ERK) Cascade in Neuronal Cell Signaling
15. Diacylglycerol Kinase (DGK)
Daniel Orellana, Ilaria Morella, Marzia Indrigo, Alessandro Papale, and Riccardo Brambilla
9. Glycogen Synthase Kinase-3 in Neurological Diseases
15. Diacylglycerol Kinase (DGK)
Oksana Kaidanovich-Beilin and James Robert Woodgett
10. Cortical Neurons Culture to Study c-Jun N-Terminal Kinase Signaling Pathway
15. Diacylglycerol Kinase (DGK)
Alessandra Sclip, Xanthi Antoniou, and Tiziana Borsello
11. MuSK: A Kinase Critical for the Formation and Maintenance of the Neuromuscular Junction
15. Diacylglycerol Kinase (DGK)
Arnab Barik and Lin Mei
12. Assays for Pten-Induced Novel Kinase 1 (PINK1) and Leucine-Rich Repeat Kinase 2 (LRRK2), Kinases Associated with Parkinson's Disease
15. Diacylglycerol Kinase (DGK)
Alexandra Beilina and Mark R. Cookson
15. Diacylglycerol Kinase (DGK)
13. Imaging PKA Activation Inside Neurons in Brain Slice Preparations
15. Diacylglycerol Kinase (DGK)
Marina Brito, Elvire Guiot, and Pierre Vincent
14. Imaging Oscillations of Protein Kinase C Activity in Cells
15. Diacylglycerol Kinase (DGK)
Maya T. Kunkel and Alexandra C. Newton
Yasuhito Shirai and Naoaki Saito
16. Trafficking of Trk Receptors
Daniel Bodmer and Rejji Kuruvilla
17. Mammalian Target of Rapamycin
Lukasz Swiech, Malgorzata Urbanska, Matylda Macias, Agnieszka Skalecka, and Jacek Jaworski
18. Protein Kinase G (PKG): Involvement in Promoting Neural Cell Survival, Proliferation, Synaptogenesis, and Synaptic Plasticity and the Use of New Ultrasensitive Capillary-Electrophoresis-Based Methodologies for Measuring PKG Expression and Molecular Actions
Ronald R. Fiscus and Mary G. Johlfs
19. Electrophysiological Technique for Analysis of Synaptic Function of PKN1 in Hippocampus
Hiroki Yasuda and Hideyuki Mukai
15. Diacylglycerol Kinase (DGK)
Yasuhito Shirai and Naoaki Saito
16. Trafficking of Trk Receptors
Daniel Bodmer and Rejji Kuruvilla
17. Mammalian Target of Rapamycin
Lukasz Swiech, Malgorzata Urbanska, Matylda Macias, Agnieszka Skalecka, and Jacek Jaworski
18. Protein Kinase G (PKG): Involvement in Promoting Neural Cell Survival, Proliferation, Synaptogenesis, and Synaptic Plasticity and the Use of New Ultrasensitive Capillary-Electrophoresis-Based Methodologies for Measuring PKG Expression and Molecular Actions
Ronald R. Fiscus and Mary G. Johlfs
19. Electrophysiological Technique for Analysis of Synaptic Function of PKN1 in Hippocampus
Hiroki Yasuda and Hideyuki Mukai
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: May, 2012
Pages: 480
Weight: 910g
Availability: Available
Subcategories: Neurology, Neuroscience, Physiology
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