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Main description:
I am pI eased to present to the readers the Proceedings of the Second International Congress on Myocardial and Cellular Bioenerge- tics and Compartmentation which was held in Los Angeles during February 16-18, 1984. I would I ike to express my deep appreciation to all those who have encouraged us to hold the Second International Congress. This endeavor could not have been possible without the generous finan- cial support of the following: The American Society for Magnesium Research, The University of Southern California Department of Con- tinuing Medical Education, Alpha Therapeutics, ALSEB Scientific Products, The American Physiological Society, Ciba-Geigy Corpora- tion, Victor Gura, M.D., Merck Sharp and Dohme, Phosphoenergetics, Stuart Pharmaceuticals, and the Upjohn Company. A note of special thanks goes to Samuel Bessman, M.D., who has been a source of constant support and encouragement for this Con- gress and for my research endeavors. Nachman Brautbar vii CONTENTS I. HICROCOMPARTHENTATION AND ENERGY TRANSPORT: The Physiological Significance of the Creatine Phosphate Shuttle ...
Contents:
I. Microcompartmentation and Energy Transport.- The Physiological Significance of the Creatine Phosphate Shuttle.- Organization of the Mitochondrial Matrix.- The Time Course of ATP Cleavage by Contracting Amphibian and Mammalian Skeletal Muscles.- Isozymes of Creatine Kinase in Mammalian Myocardial Cell Culture.- Microcompartmentation at the Mitochondrial Surface: Its Function in Metabolic Regulation.- The Effect of Inorganic Phosphate on Mitochondrial Creatine Kinase.- Hormonal Regulation of Creatine Kinase BB.- Compartmentation of Adenine Nucleotides and Phosphocreatine Shuttle in Cardiac Cells: Some New Evidence.- Compartmentation of Hormone Action in Adult Mammalian Cardiomyocytes.- Function of Creatine Kinase Localization in Muscle Contraction.- Isotope Labeling Ratios: A Tool for the Exploration of Metabolic Compartments.- The Mitochondrial Creatine Phosphokinase is Associated with Inner Membrane Cardiolipin.- A Role for Mitochondria in Myocardial Adenosine Production.- II. Respiration Control - Cellular and Organ Level.- Aspects of Heart Respiratory Control by the Mitochondrial Isozyme of Creatine Kinase.- Control of Respiration in Intact Muscle.- Energy Compartmentation and Active Transport in Proximal Kidney Tubules.- The Oxygen Dependence of Cellular Energy Metabolism.- Regulation of Mitochondrial Respiration in Liver.- Quantitation of Fluxes in the Gluconeogenic, Glycolytic, and Pentose Phosphate Pathways in Isolated Rat Hepatocytes: Energetic Considerations.- Why is There a Delay in the Increased Oxygen Consumption During the Rest-Work Transition in Skeletal Muscles.- III. Myocardial Preservation, Ischemia: Cellular Mechanisms.- Compartmentation and Functional Mechanisms in Myocardial Failure and Myocardial Infarction.- Myocardial Protection of Hypertrophied Hearts by Administration of Cardioplegia According to Regional Myocardial Temperature.- Heart Myocytes as Models of the Cellular Response to Ischemia.- Biologic Basis for Limitation of Infarct Size.- Mitochondrial Transmembrane Proton Electrochemical Potential, Di- and Tricarboxylate Distribution and the Poise of the Malate-Aspartate Cycle in the Intact Myocardium.- Sarcomere Length-tension Relationship in Toad Atrioventricular Pacemaker: Length Dependent Activation.- Myocardial Acidosis and the Mitigation of Tissue ATP Depletion in Ischemic Cardiac Muscle: The Role of the Mitochondrial ATPase.- Vascular Metabolism and Energetics.- Myocardial Glutamate Dehydrogenase Activity.- Long Term Model for Evaluation of Myocardial Metabolic Recovery Following Global Ischemia.- The Effect of Reperfusion and Streptokinase on Ischemic Myocardium Serum Creatine Kinase Activity, MM Subtypes and Myocardial Blood Flow.- Post-contracture Reperfusion: Effect of Elevated Potassium and Verapamil.- Ultrastructure of the Human Myocardium after Intermittent Ischemia Compared to Cardioplegia.- IV. Pathophysiology of Energy Compartmentation.- Cellular Injury in Phosphate Depletion: Pathogenesis and Mechanisms in the Myocardium.- Diabetes Mellitus and Hypothyroidism Induce Changes in Myosin Isoenzyme Distribution in the Rat Heart - Do Alterations in Fuel Flux Mediate These Changes?.- Glycerol Kinase Deficiency: Compartmental Considerations Regarding Pathogenesis and Clinical Heterogeneity.- Phosphorylated Nucleotides and Glycolytic Intermediates in Diabetic and Non-diabetic Rat uterus in Late Pregnancy.- Effect of Calcium Antagonists on Vasopressin Induced Changes in Myocardial and Renal Pyridine Nucleotides in the Intact Rat.- The Effect of Creatine Analogue Substitution on the Post Tetanic Response of Fast Muscle.- V. Divalent Ions and Cellular Bioenergetics.- Calcium Compartmentation in Mammalian Myocardium.- Calcium Channel Blockers, Beta Blockers and the Maintenance of Calcium Homeostasis.- Sodium-Calcium Exchange: Calcium Regulation at the Sarcolemma.- The Calcium Pumping ATPase of Heart Plasma Membrane.- Calcium Compartmentation and Regulation in Myocytes.- Ca++-Dependent and Ca++-Independent Effects of Mg++ on Canine Right Atria.- Chronotropic and Inotropic Effects of [Mg++]o Not Dependent upon [Ca++]o.- Sodium Modulation of Resting Force, Contractile Properties, and Metabolism with Particular Emphasis on its Role in the Development of Calcium Overload States.- The Effect of Short Chain Fatty Acid Administration on Hepatic Glucose, Phosphate, Magnesium and Calcium Metabolism.- VI. 31-P NMR.- Lessons for Muscle Energetics from 31P NMR Spectroscopy.- Metabolic Depletion Preceding Cytolysis Induced by Antibody and Complement as Revealed by 31P-NMR Spectroscopy.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: April, 2012
Pages: 692
Weight: 1303g
Availability: Available
Subcategories: Cardiovascular Medicine
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