(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
Apoptosis is a fascinating concept for the basic scientist. This is not only because of the multifaceted variety of proposed and discovered mechanisms, but because apoptosis represents a fundamental pathway for cell renewal. The study of apoptosis has resulted in an array of discoveries on signal transduc tion and downstream effects that have facilitated and advanced many fields in biology, including research on cancer and other diseases. Thus, the apoptotic process can be viewed as the largest effort of the scientific community to understand how cells work and tissues assemble or remodel. The most direct consequence of this accumulated knowledge is a greater understanding of disease and pathological mechanisms. The end result of these efforts will be significant contributions to health and the adoption of new, never anticipated, therapeutic approaches. This book represents the summation of considerable effort from a significant group of contributors from all over the world as well as from its editors. In this fashion, many viewpoints have been collected and SUbjected to thorough academic discussion. The concepts contained in this medically important volume will stimulate and renew the ideas of scientists and indeed, will generate additional work to advance biological knowledge even further. The emphasis of this volume cements what has been established, adds what has not been explored fully, and creates a fertile ground for further hypotheses that will lead to a more complete understanding of the apoptotic process.
Contents:
1 Incidence of Apoptosis and Its Pathological and Biochemical Manifestations.- 2 Molecular Cellular and Tissue Reactions of Apoptosis and Their Modulation by Drugs.- 3 Hepatocyte Apoptosis Triggered by Natural Substances (Cytokines, Other Endogenous Molecules and Foreign Toxins).- 4 The Role of C-type Protein Kinases in Apoptosis.- 5 How Does Programmed Cell Death Contribute to AIDS Pathogenesis?.- 6 Apoptotic Cell Phagocytosis.- 7 T Cell Apoptosis and Its Role in Peripheral Tolerance.- 8 Apoptosis of Nerve Cells.- 9 Use of p53 as Cancer Cell Target for Gene Therapy.- 10 Antioxidants: Protection Versus Apoptosis.- 11 Reactive Oxygen Species and Apoptosis.- 12 Clearance of Apoptotic Lymphocytes by Human Kupffer Cells. Phagocytosis of Apoptotic Cells in the Liver: Role of Lectin Receptors, and Therapeutic Advantages.- 13 Drug-Induced Apoptosis of Skin Cells and Liver.- 14 Apoptosis and Eosinophils.- 15 Thymocyte and B-Cell Death Without DNA Fragmentation.- 16 Antigen Receptor-Induced Death of Mature B Lymphocytes.- 17 Modulation of Apoptosis and Maturation of the B-Cell Immune Response.- 18 The Neuroprotective and Neuronal Rescue Effect of (-)-Deprenyl.- References.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: November, 2012
Pages: 478
Weight: 771g
Availability: Available
Subcategories: Anatomy, Immunology, Neuroscience, Oncology, Pathology, Pharmacology, Physiology
From the same series
Roger G. Pertwee
Philip K. Moore
Kathleen M. Kantak
Alan Cowan
Hans-Georg Schaible
Arnold von Eckardstein
Mark A. Geyer
Botond Berde
Lorenzo A. Pinna
Arnold von Eckardstein
Mark A. Geyer
Anthony R.M. Coates
Vera Regitz-Zagrosek
Ursula F. Habenicht
Christoph Stein
Fabrizio Benedetti
Paolo Gresele
O. Eichler
Clive P. Page
Peter Ruben
G. Peters
Gary R. Lewin
Allison D. Fryer
Hans-Georg Joost
Vsevolod V. Gurevich
Hannsjorg W. Seyberth
Sharron H. Francis
George B. Koelle
Marc Humbert
G Kimmerle
Martha Merrow
Erich Gulbins
Martin C. Michel
Mathias Schwanstecher
Erich Gulbins
Martin F. Fromm
Hanns Mohler
Mark A. Geyer
F. Clementi
Peter Holzer
Gaetano Di Chiara
Anthony R. M. Coates
David S. Latchman
Siamon Gordon
Bernard Testa
Michael Oettel
B. Mayer
Klaus, von der Helm
Sheldon H. Preskorn
Lutz Hein
Heinz Nau
Stanley T. Crooke
J.M. Monti
Martin C. Michel
Vera Regitz-Zagrosek
Mark A. Geyer
G. Peters
Paolo Gresele
Manfred Gossen
Maynard B. Chenoweth
W. McD. Armstrong
Clive P. Page
Monika Schafer-Korting
Detlef Thieme
Fiona Cunningham
Vittorio Erspamer
Hans H. Ussing
Oskar Eichler
Ervin G. Erdös
S. Bettini
R.E.M. Bowden
John Morley
P.S. Randall
H. Winkler
R Jahn
J. Harenberg
F. Bachmann
D.J. Atherton
M.T. Jones
Frank A. Smith
Timothy D. Warner
Jochen Kuhlmann
James R. Gillette
Joel Bockaert
M. Chatterjee
A.P. Weetman
M. Sovak
Clive P. Page
James William Fisher
Hans-Georg Joost
D.I. Abramson
H.P. Witschi
R. Assan
Alfred J. Clark
J.M. van Rossum
Helmut Greim
Allison D. Fryer
Michael Oettel
M.L. Sears
R. Hess
P.E. Came
C.F. Arlett
H. Mehnert
W.N. Kelley
Luc P. Balant
Alan C. Sartorelli
Gregory R. Mundy
W. R. Martin
Peter Perlman
Michael B. Sporn
Harold C. Hodge
David R. Brown
C. Muller
J. Erik Jorpes
H.E. Voss
Peter Frederick Baker
Pedro Cuatrecasas
Laszlo Szekeres
Fritz Markwardt
R. Baserga
D.A. Kharkevich
H. Vanden Bossche
Stephen H. Caldwell
Ronald T. Borchardt
Alain L. de Weck
Lawrence E. Bryan
T.J. Campbell
F. Lang
K. Bartmann
Donald B. Calne
E.M. Johnson
G.H. Hitchings
Arnold L. Demain
Eugen Dorzbach
U. Peters
M. Green
A. S. Milton
R. Baurain
Brian W. Fox
W. Bleifeld
P. Actor
H. Vanden Bossche
Victor P. Whittaker
Ullrich Trendelenburg
D. Janz
Börje Uvnäs
H.G. Baumgarten
J. A. Nathanson
Frederick C. Kauffman
S. Silver
Kurt Greeff
B. Babudieri
J.G. Banwell
T.T. Aoki
A.L. Jr. Ager
M. Ackenheil
M. Rocha e Silva
Carlo Patrono
Hamao Umezawa
W. Rogalski
G. R. Strichartz
E.C. Foulkes
P. Needleman
E. Anggard
H. Schmidt
C. Braestrup
L.G. Abood
D.A. Kharkevich
C.-Y. Lee
Charles D. Kochakian
Robert Charlier
A.C. Allison
I.H. Page
James R. Gillette
Hermann Blaschko
K.W. Bock
Dean H. Lockwood
A. Dickenson
Franz von Bruchhausen
P.F. D'Arcy
Robert J. Kavlock
Andrew C.G. Uprichard
P.J. Lefebvre
Mervyn J. Eadie
Franz Hefti
Ross G. Cameron
John G. Csernansky
Michael J. Kuhar
Hannsjorg W. Seyberth
Sharron H. Francis
Mathias Schwanstecher
Martin C. Michel
Martin R. Wilkins
Martin F. Fromm
Peter Redfern
Klaus Aktories
Jurgen Behrens
Harri U. Vainio
Michael Williams
Dennis W. Choi
Gaetano Di Chiara
Peter Jonas
Salvador Moncada
Stefan Bauer
Markus Schwaiger
Markus Schwaiger
Jurgen Schuttler
Hans-Georg Krausslich
Veit M. Flockerzi
Harald H.H.W. Schmidt
Thomas C. Sudhof
Eric Beitz
Kian Fan Chung
Andreas Michael Zeiher
Yuti Chernajovsky
Jack E. Henningfield
Giovanna Lombardi
Salvador Moncada
Florian Holsboer
Enno Klussmann
Clive P. Page
Bertil B. Fredholm
Ursula F. Habenicht
Fiona Cunningham
Monika Schafer-Korting
Matthias Gaestel
Volker A. Erdmann
Robert E. Kass
Harald Sitte
Detlef Thieme
Domenico Spina
Constance N. Wilson
Jack E. Henningfield
Eric Beitz
Harald H.H.W. Schmidt
Giovanna Lombardi
Hans-Georg Krausslich
Kian Fan Chung
Markus Schwaiger
Markus Schwaiger
Enno Klussmann
Anna M. Wobus
Jurgen Schuttler
Thomas C. Sudhof
Stefan Bauer
Yuti Chernajovsky
Andreas Michael Zeiher
Veit M. Flockerzi
Christoph Stein
Salvador Moncada
Salvador Moncada
Harald Sitte