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Cushing's Syndrome
Pathophysiology, Diagnosis and Treatment
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Main description:

Cushings syndrome is a relatively rare clinical disorder that is associated with many co-morbidities such as systemic hypertension, diabetes, osteoporosis, impaired immune function and growth impairment in children, all of which severely reduce quality of life and life expectancy. Cushing's Syndrome: Pathophysiology, Diagnosis and Treatment reviews the difficulties in distinguishing Cushing's syndrome from these and other common conditions, such as central obesity, menstrual irregularity and depression. It also provides state-of-the-art information on various strategies to establish the diagnosis of Cushing's syndrome and the differential diagnosis among its diverse etiologies, as well as therapeutic approaches. Additionally, a range of conditions that represent challenges for the diagnosis and treatment--such as renal failure, pediatric age, cyclic hypercortisolism, and pregnancy--are covered in detail. A valuable resource not only for endocrinologists but also internal medicine physicians, gynecologists, pediatricians, , pituitary surgeons and urologists, Cushing's Syndrome: Pathophysiology, Diagnosis and Treatment provides insights by experts that will help all physicians dealing with Cushings syndrome to expand their knowledge about the condition and provide targeted, comprehensive care.


Contents:

Chapter 1: Physiology and Pathophysiology of the HPA axis, by Margareth Castro and Ayrton Custodio Moreira

Chapter 2: Etiologies of Cushings syndrome, by John Newell-Price

Chapter 3: Pathogenesis of corticotropic tumors, by Shlomo Melmed

Chapter 4: Pathogenesis of adrenocortical tumors, by Madson Q. Almeida, Emilia M. Pinto, and Ana Claudia Latronico

Chapter 5: Clinical features of Cushings syndrome, by Oscar Bruno

Chapter 6: Laboratorial diagnosis of Cushings Syndrome: Differential diagnosis with pseudo-Cushings conditions as obesity, alcoholism and depression, by Francesco Cavagnini

Chapter 7: Laboratorial diagnosis of Cushings syndrome: Differential diagnosis among the different causes of ACTH-dependent and ACTH-independent Cushings syndrome, by Antonio M. Lerario and Marcello D.Bronstein

Chapter 8: Imaging for the differential diagnosis of Cushings syndrome: MRI, CT and isotopic scanning, by Wouter de Herder

Chapter 9: Inferior petrosal sampling for the differential diagnosis of ACTH dependent Cushings syndrome, by James W. Findling and Bradley Javorsky

Chapter 10: ACTH-dependent Cushing syndrome: Treatment of Cushings disease
A) Treatment of Cushings Syndrome: Surgical Treatment, by Edward Laws
B) Adrenal-Directed Treatment Options for Cushing's Disease, by William Young
C) Radiation Therapy and Stereotactic Radiosurgery for Cushing's Disease, by Jason P Sheehan
D) Medical Management of Cushing's syndrome, by Peter Trainer

Chapter 11: ACTH-dependent Cushing syndrome: Clinical and diagnostic aspects, and treatment approaches for ectopic Cushings syndrome, by Ashley Grossman

Chapter 12: Revisiting the Nelson's syndrome: Corticotroph Tumor Progression after bilateral adrenalectomy in Cushing's disease, by Xavier Bertagna

Chapter 13: ACTH-independent Cushings syndrome: Adrenocortical tumors, by Maria Candida Fragoso, Ana Claudia Latronico and Berenice B. Mendonca

Chapter 14: ACTH-independent Cushings syndrome: Bilateral macronodular hyperplasia, by Andre Lacroix

Chapter 15: ACTH-independent Cushings syndrome: primary pigmented nodular adrenal disease in the context of Carneys complex, by Constantine A Stratakis

Chapter 16: Glucocorticoid Resistance, by Elisabeth F.C. van Rossum and Steven W. Lamberts

Chapter 17: Post-operative replacement and assessment of HPA axis recovery in Cushing's syndrome, by John Wass

Chapter 18: Special aspects of Cushings syndrome: Pregnancy, by David Aron

Chapter 19: Special aspects of Cushings syndrome: Childhood, by M. O. Savage

Chapter 20: Special aspects of Cushings syndrome: Cyclic Cushings syndrome, by Franco Mantero


PRODUCT DETAILS

ISBN-13: 9781617797095
Publisher: Springer (Humana Press Inc.)
Publication date: December, 2012
Pages: 316
Weight: 669g
Availability: Available
Subcategories: Diseases and Disorders, Endocrinology, Neurosurgery, Obstetrics and Gynaecology, Oncology, Paediatrics and Neonatal
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