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Stem Cells in Endocrinology
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Main description:

A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders.


Contents:

Part I: Basic Stem Cell Biology

Embryonic Stem Cells: Derivation, Properties, and Therapeutic Implications
Victoria L. Browning and Jon S. Odorico

Germ Line Stem Cells
Makoto C. Nagano

Umbilical Cord Stem Cells
Kathy E. Mitchell

Differentiation Potential of Adult Stem Cells
Henry E. Young and Asa C. Black, Jr.

Growth Conditions for Primate vs Murine Embryonic Stem Cells
Gillian M. Beattie, Nathan Bucay, Rohan Humphrey, Ana D. Lopez, and Alberto Hayek

Part II: Translational Research

Islet Precursor Cells in Adult Pancreatic Islets
Gladys Teitelman and Irem Nasir

Transcription Factor-Directed Differentiation of Stem Cells Along an Endocrine Lineage
William L. Lowe, Jr.

Generation of Islet-Like Structures From ES Cells
Nadya Lumelsky

The Therapeutic Potential of Liver Repopulation for Metabolic or Endocrine Disorders
Sanjeev Gupta

The Manipulation of Mesenchymal Stem Cells for Bone Repair
Shelley R. Winn

Spermatogenesis From Transplanted Spermatogenic Stem Cells
Michael D. Griswold and Derek McLean

Hematopoietic Stem Cell Transplant in the Treatment of Autoimmune Endocrine Disease
Jody Schumacher and Ewa Carrier

Preclinical Trials for Stem Cell Therapy
Linda B. Lester, K. Y. Francis Pau, and Don P. Wolf

Index


PRODUCT DETAILS

ISBN-13: 9781617375477
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2010
Pages: 288
Weight: 427g
Availability: Available
Subcategories: Endocrinology
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