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Endocrine Disruptors and Puberty
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Main description:

Endocrine disruption represents one of the most controversial environmental issues of our time. Mounting evidence stemming from more than 10 years of experimental, epidemiological and clinical studies has transformed the once generally discounted subject of endocrine disruptors into an issue of tremendous concern not only within the scientific community but among society as a whole. Following initial evidence from basic research, endocrine disruption in humans has now emerged as a major medical challenge. In this respect, puberty, a crucial developmental stage, has been definitively identified as a key window of vulnerability with regard to endocrine disruptors. Written by leading authorities in the field, Endocrine Disruptors and Puberty offers an engaging and comprehensive overview of this fascinating and rapidly growing problem. An indispensable resource for all clinicians and scientists interested in this challenging endocrinologic topic, Endocrine Disruptors and Puberty is a timely contribution that will help navigate a path toward understanding the problem and developing solutions.


Contents:

1 Introduction to endocrine disruptors and Puberty
Evanthia Diamanti-Kandarakis
Andrea C. Gore

Part I: EDCs, endocrine systems, and puberty
2 In utero exposure to environmental chemicals - Lessons from maternal cigarette smoking and its effects on gonad development and puberty
Rebecca McKinlay
Peter O'Shaughnessey
Richard M. Sharpe
Paul A. Fowler

3 Reproductive Neuroendocrine Targets of Developmental Exposure to Endocrine Disruptors
Sarah M. Dickerson
Stephanie L. Cunningham
Andrea C. Gore

4 Endocrine disruptors and puberty disorders from mice to men (and women)
Alberto Mantovani

5 Thyroid hormone regulation of mammalian reproductive development and the potential impact of endocrine disrupting chemicals
Kara Renee Thoemke
Thomas William Bastian
Grant Wesley Anderson

Part II: Developmental exposure to endocrine disruptors and adverse reproductive outcomes
6 Developmental exposure to endocrine disruptors and ovarian function
Evanthia Diamanti-Kandarakis
Eleni Palioura
Eleni A.Kandaraki

7 Developmental exposure to environmental endocrine disruptors and adverse effects on mammary gland development
Suzanne Fenton
Lydia M. Beck
Aditi R. Borde
Jennifer Rayner

8 Developmental exposure to endocrine disruptors and male urogenital tract malformations
Mariana F. Fernandez
Nicolas Olea, MD PhD

9 EDC exposures and the development of reproductive and non-reproductive behaviors
Amy B. Wisniewski
Craige C. Wrenn
Ashwini Mallappa

Part III. Developmental exposure to endocrine disruptors and metabolic disorders
10 Adipocytes as target cells for endocrine disruption
Amanda Janesick
Bruce Blumberg

11 Altered Glucose Homeostasis Resulting From Developmental Exposures To Endocrine Disruptors
Alan Schneyer
Melissa Brown

12 Developmental Exposure to Endocrine Disrupting Chemicals: Is there a Connection with Birth and Childhood Weights?
Elizabeth E. Hatch
Jessica W Nelson
Rebecca Triosi
Linda Titus

Part IV. EDCs and Human Health
13 The Impact Of Endocrine Disruptors On Female Pubertal Timing
Jean-Pierre Bourguignon
Anne-Simone Parent

14 The influence of endocrine disruptors on Male Pubertal Timing
Xiu-feng Wu
Ningning Zhang
Mary M. Lee

15 Secular Trends in Pubertal Timing: A Role for Environmental Chemical Exposure?
Vincent F. Garry
Peter Truran, PhD


PRODUCT DETAILS

ISBN-13: 9781627039222
Publisher: Springer (Humana Press Inc.)
Publication date: March, 2014
Pages: 378
Weight: 605g
Availability: Available
Subcategories: Diseases and Disorders, Endocrinology, Oncology, Pharmacology
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