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Main description:
A panel of expert clinical and basic investigators summarize the state-of-the-art in the use of transgenic technology in a broad range of endocrinological applications. Up-to-date and comprehensive, Transgenics in Endocrinology reviews the most recent developments in the analysis of endocrine physiology and its pathologies through mouse models, and provides a host of creative approaches to understand better the complex processes that are characteristic of hormonal systems.
Contents:
Germline Genetic Engineering Techniques in Endocrinology
Albert S. Y. Chang, Michael J. Reardon, and Francesco J. DeMayo
The Transgenic Mouse in Studies of Mammalian Sexual Differentiation
Deanne J. Whitworth and Richard R. Behringer
The In Vivo Function of Mullerian-Inhibiting Substance During Mammalian Sexual Development
Yuji Mishina
Control of Ovarian Function
Julia A. Elvin and Martin M. Matzuk
Mouse Models to Study the Pituitary-Testis Interplay Leading to Regulated Gene Expression
Emiliana Borrelli, T. Rajendra Kumar, and Paolo Sassone-Corsi
Functional Analysis of the Bcl2 Gene Family in Transgenic Mice
Andrea J. Ross and Grant R. MacGregor
The Role of C-Kit/Kit Ligand Axis in Mammalian Gametogenesis
Peter J. Donovan and Maria P. de Miguel
Gene Knockout Approaches to Steroidogenesis
Tomonobu Hasegawa, Liping Zhao, Kathleen M. Caron, Morag Young, and Keith L. Parker
The Progesterone Receptor Knockout Mouse Model: New Insights into Progesterone Action In Vivo
John P. Lydon, Selma Soyal, Bert W. O'Malley, Preeti M. Ismail
Knockout and Transgenic Mouse Models that Have Contributed to the Understanding of Normal Mammary Gland Development
Tiffany N. Seagroves and Jeffrey M. Rosen
Prolactin and the Prolactin Receptor
Nelson D. Horseman
Transgenic Models for Oxytocin and Vasopressin
Larry J. Young and Thomas R. Insel
Glycoprotein Hormones: Transgenic Mice as Tools to Study Regulation and Function
Ruth A. Keri and John H. Nilson
Genetic Approaches to the Study of Pituitary Follicle-Stimulating Hormone Regulation
Daniel J. Bernard and Teresa K. Woodruff
Transgenic Analysis of the Proopiomelanocortin Neuroendocrine System
Malcolm J. Low, Marcelo Rubinstein, and E. Cheng Chan
Overexpression and Targeted Disruption of Genes Involved inthe Control of Growth, Food Intake, and Obesity
Andrzej Bartke and Michael Michalkiewicz
Insulin and Insulin-Like Growth Factors: Targeted Deletion of the Ligands and Receptors
Carolyn A. Bondy and Domenico Accili
Use of Transgenic Animals in Skeleton Biology
Thomas Gunther, Mary Jo Doherty, and Gerard Karsenty
Transgenic Mouse Models of Prostate Cancer
Robert J. Matusik, Naoya Masumori, Tania Thomas, Thomas Case, Manik Paul, Susan Kasper, and Scott B. Shappell
Neural- and Endocrine-Cell-Specific Immortalization Using Transgenic Approaches
T. Rajendra Kumar
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: December, 2012
Pages: 486
Weight: 935g
Availability: Available
Subcategories: Endocrinology
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