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MORE ABOUT THIS BOOK
Main description:
Gerald Reaven, the discoverer of Syndrome X, and a panel of world-class investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease-the so-called diseases of Western civilization. These distinguished authorities detail, for the first time, the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Timely and authoritative, Insulin Resistance: The Metabolic Syndrome X illuminates the full importance of insulin resistance as a major cause of hypertension, heart disease, and polycystic ovary syndrome.
Contents:
Part I. Genetic and Environmental Factors Affecting Insulin Action. Genetics of Insulin Resistance, Michael P. Stern and Braxton D. Mitchell. Ethnic Variation in Insulin Resistance and Risk of Type 2 Diabetes, Paul M. McKeigue. Fetal Effects on Insulin Resistance and Glucose Tolerance,Paul M. McKeigue. Obesity and Insulin Resistance: Epidemiologic, Metabolic, and Molecular Aspects, Jean-Pierre Despres and Andre Marette. The Role of Body Fat Distribution in Insulin Resistance, Abhimanyu Garg. Physical Activity and Insulin Resistance in Man, Flemming Dela, Kari Mikines, and Henrik Galbo. Insulin Resistance in Smokers and Other Long-Term Users of Nicotine, Bjoern Eliasson and Ulf Smith. Part II. Pathophysiology of Insulin Resistance. Insulin Resistance and Inhibitors of Insulin Receptor Tyrosine Kinase, Jack F.Youngren, Ira D. Goldfine, Vincenzo Trischitta, and Betty A. Maddux. NMR Studies on the Mechanism of Insulin Resistance, Gianluca Perseghin, Kitt Falk Petersen, and Gerald I. Shulman. Skeletal Muscle Insulin Resistance in Humans: Cellular Mechanisms, Lawrence J. Mandarino. The Role of the Liver in Insulin Action and Resistance, Jerry Radziuk and Susan Pye. The Pathophysiological Consequences of Adipose Tissue Insulin Resistance, Gerald M. Reaven. Insulin Action and Endothelial Function, Alain D. Baron and Michael J. Quon. Part III. Clinical Syndromes Associated with Insulin Resistance. Insulin Resistance and Dyslipidemia: Implications for Coronary Heart Disease Risk, Ami Laws. Insulin Resistance and Blood Pressure, Ele Ferrannini. Microalbuminuria and Insulin Resistance, Jeannie Yip and Roberto Trevisan. PAI-1, Obesity, and Insulin Resistance, Irene Juhan-Vague, Marie-Christine Alessi, and Pierre E. Morange. Insulin Resistance and Cardiovascular Disease, Aaron R. Folsom. Insulin Resistance Effects on Sex Hormones and Ovulation in the Polycystic Ovary Syndrome, John E. Nestler. Index.
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: November, 2010
Pages: 384
Weight: 736g
Availability: Available
Subcategories: Endocrinology
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