Main description:

50 Studies Every Doctor Should Know presents key studies that have shaped the practice of medicine. Selected using a rigorous methodology, the studies cover topics ranging from dieting to cardiovascular disease, insomnia to obstetrics. For each study, a concise summary is presented with an emphasis on the results and limitations of the study, and its implications for practice. Brief information on other relevant studies is provided, and an illustrative clinical case
concludes each review. A section of review questions and answers is included at the back of the book to ensure that readers take away the key messages from each study. This book is a must-read for health care professionals and anyone who wants to learn more about the data behind clinical
practice.

Contents:

Section 1: Preventive Medicine ; 1. Preventing Diabetes: The Diabetes Prevention Program ; 2. A Comparison of Different Dieting Strategies ; 3. Aspirin for the Primary Prevention of Cardiovascular Disease: The Physicians' Health Study and the Women's Health Study ; 4. Postmenopausal Hormone Therapy: The Women's Health Initiative ; 5. The European Randomized Study of Screening for Prostate Cancer (ERSPC) ; 6. The Cochrane Review of Screening Mammography ; 7. The Human Papillomavirus Vaccine: The Future II Trial ; Section 2: Internal Medicine ; 8. Arrhythmia Suppression Following Myocardial Infarction: The CAST Trial ; 9. Choosing First-Line Therapy for Hypertension: The ALLHAT Trial ; 10. Statins in Healthy Patients with an Elevated C-Reactive Protein: The JUPITER Trial ; 11. Rate vs. Rhythm Control for Atrial Fibrillation: The AFFIRM Trial ; 12. Lenient vs. Strict Heart Rate Control for Atrial Fibrillation: The RACE II Trial ; 13. Beta-Blockers for Systolic Heart Failure: The MERIT-HF Trial ; 14. Initial Treatment of Stable Coronary Artery Disease: The COURAGE Trial ; 15. Treating Elevated Blood Sugar Levels in Patients with Type 2 Diabetes: The United Kingdom Prospective Diabetes Study (UKPDS) ; 16. Intensive vs. Conservative Blood Sugar Control for Patients with Type 2 Diabetes: The ACCORD Trial ; 17. The African American Heart Failure Trial (A-HeFT) ; 18. Early vs. Delayed Antiretroviral Therapy for Patients with HIV: The NA-ACCORD Study ; 19. Early vs. Late Initiation of Dialysis: The IDEAL Trial ; 20. Early Goal-Directed Therapy in Sepsis ; 21. Red Cell Transfusion in Critically Ill Patients: The TRICC Trial ; 22. Pulmonary Artery Catheters in Critically Ill Patients ; 23. Step-Up vs. Step-Down Therapy for Dyspepsia: The DIAMOND Trial ; 24. Opioids for Chronic Non-Cancer Pain ; Section 3: Surgery ; 25. Perioperative Beta-Blockers in Non-Cardiac Surgery: The POISE Trial ; 26. Cardiac Stents vs. Coronary Artery Bypass Surgery for Severe Coronary Artery Disease: The SYNTAX Trial ; 27. Carotid Endarterectomy for Asymptomatic Carotid Stenosis: The ACST Trial ; 28. A Trial of Arthroscopic Knee Surgery ; 29. Surgery vs. Rehabilitation for Chronic Low Back Pain: The MRC Spine Stabilization Trial ; 30. Mastectomy vs. Lumpectomy for Invasive Breast Cancer: The B-06 Trial ; 31. Long Term Impact of Bariatric Surgery: The Swedish Obese Subjects Study ; Section 4: Obstetrics ; 32. The Canadian Multicenter Post-term Pregnancy Trial (CMPPT) ; 33. Antepartum Glucocorticoids in Premature Labor ; Section 5: Pediatrics ; 34. Treatment of Acute Otitis Media in Children ; 35. A Trial of Early Ear Tube Placement in Children ; 36. Inhaled Corticosteroids for Mild Persistent Asthma: The START Trial ; 37. The Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder (MTA) ; 38. Measles, Mumps, and Rubella Vaccination and Autism ; Section 6: Radiology ; 39. Magnetic Resonance Imaging for Low Back Pain ; 40. Screening for Coronary Artery Disease in Asymptomatic Patients with ; Diabetes: The DIAD Study ; 41. Diagnosing Acute Pulmonary Embolism: The Christopher Study ; 42. Identifying Children with Low-Risk Head Injuries Who Do Not Require ; Computed Tomography ; Section 7: Neurology and Psychiatry ; 43. Thrombolysis 3 to 4.5 Hours After an Acute Ischemic Stroke: The ECASS III ; Trial ; 44. Initial Treatment of Depression ; 45. Behavioral vs. Pharmacological Treatment for Insomnia in the Elderly ; Section 8: Systems Based Practice ; 46. The Group Health Medical Home Demonstration ; 47. A Program to Improve Care Coordination at Hospital Discharge: Project RED ; 48. Reducing Catheter-Related Blood Stream Infections in the Intensive Care Unit: The Keystone ICU Project ; 49. Early Palliative Care in Non-Small-Cell Lung Cancer ; 50. Directly Observed Therapy for the Treatment of Tuberculosis in Baltimore ; Section 9: Study Questions and Answers