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MORE ABOUT THIS BOOK
Main description:
Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology-from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
Contents:
Preface.- Understanding the Logic of I B:NF- B Regulation in Structural Terms.- NF- B/Rel proteins and the humoral immune responses of Drosophila melanogaster.- Specialized chromatin patterns in the control of inflammatory gene expression.- IKK regulation and human genetics.- Control of NF- B activity by proteolysis.- NF- B and Innate Immunity.- NF- B and mucosal homeostasis.- IKK and NF- B mediated functions in carcinogenesis.- Macrophages and NF- B in Cancer.- NF-kappaB in liver cancer - the plot thickens.- NF-kappaB as a target for oncogenic viruses.- Inhibition of NF- B signaling as a strategy in disease therapy.- Subject index
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: July, 2013
Pages: 276
Weight: 427g
Availability: Available
Subcategories: Genetics, Oncology, Physiology
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