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Antibodies in Viral Infection
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Main description:

Antibodies are central to vaccines and it is becoming increasingly apparent that understanding how antibodies combat viruses could be crucial in a new era of vaccine development. This book describes the state of the art in explaining the anti-viral activity of antibodies at the molecular level, with chapters from many of the leaders in the field.


Contents:

Antibody interactions with rhinovirus lessons for mechanisms of neutralization and the role of immunity in viral evolution.- Structural studies on antibody with viruses.- Shape and electrostatic complementarity at viral antigen-antibody complexes.- Structural studies on viral escape from antibody neutralization.- Affinity, complementarity, cooperativity, and specificity in antibody recognition.- Mechanisms of virus neutralization by antibody.- Neutralization of viruses is achieved by antibody coating of the virion surface.- Anti-mediated enhancement of viral disease.- The role of antibody response in influenza virus infection.- Role of antibodies in controlling alphavirus infection of neurons.- Role of mucosal antibodies in viral infections.- The role of the complement system in virus infection.- Intrabodies as anti-viral agents.- T-bodies as anti-viral agents.- Subject index.


PRODUCT DETAILS

ISBN-13: 9783642074868
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: December, 2010
Pages: 320
Weight: 498g
Availability: Available
Subcategories: Immunology, Microbiology
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