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MORE ABOUT THIS BOOK
Main description:
This two-volume work covers the molecular and cell biology, genetics and evolution of influenza viruses, the pathogenesis of infection, resultant host innate and adaptive immune response, prevention of infection through vaccination and approaches to the therapeutic control of infection.. Experts at the forefront of these areas provide critical assessments with regard to influenza virology, immunology, cell and molecular biology, and pathogenesis. Volume I provides overviews of the latest findings on molecular determinants of viral pathogenicity, virus entry and cell tropism, pandemic risk assessment, transmission and pathogenesis in animal species, viral evolution, ecology and antigenic variation, while Volume II focuses on the role of innate and adaptive immunity in pathogenesis, development of vaccines and antivirals.
Contents:
Part I: Innate immunity
The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options
John R. Teijaro
Innate immune sensing and response to influenza
Mohan S. Maddur and Bali Pulendran
The NS1 protein: a multitasking virulence factor
Juan Ayllon and Adolfo Garcia-Sastre
Role of NK cells in influenza infection
Stacey Shultz-Cherry
Host detection and the stealthy phenotype in influenza virus infection
Pradyot Dash and Paul G. Thomas
Part II: Vaccines and adaptive immunity
Inactivated and adjuvanted influenza vaccines
Giuseppe Del Giudice and Rino Rappuoli
Live attenuated influenza vaccine
Hong Jin and Kanta Subbarao
Design of alternative live attenuated influenza virus vaccines
Courtney Finch, Weizhong Li and Daniel R. Perez
Rapid production of synthetic influenza vaccines
Philip R. Dormitzer
Influenza neuraminidase as a vaccine antigen
Maryna C. Eichelberger and Hongquan Wan
Advances in universal influenza virus vaccine design and antibody mediated therapies based on conserved regions of the hemagglutinin
Florian Krammer, Peter Palese and John Steel
Structural characterization of epitopes recognized by broadly cross-reactive antibodies
Peter S. Lee and Ian A. Wilson
Skin immunization with influenza vaccines
Ioanna Skountzou and Richard W. Compans
Mucosal immunization and adjuvants
Hideki Hasegawa, Elly van Reit and Hiroshi Kida
B cell responses to infection and vaccination
Christopher Chiu, Ali Ellebedy, Jens Wrammert and Rafi Ahmed
Memory CD4 T cells in influenza
Kyra D. Zens and Donna L. Farber
The effector T cell response to influenza infection
Matthew M. Hufford, Taeg S. Kim, Jie Sun and Thomas J. Braciale
Part III: New antiviral discovery
Antiviral Effects of Inhibiting Host Gene Expression
Ralph A. Tripp and S. Mark Tompkins
PRODUCT DETAILS
Publisher: Springer (Springer International Publishing AG)
Publication date: November, 2014
Pages: 400
Weight: 8572g
Availability: Available
Subcategories: Immunology, Infectious Diseases, Microbiology, Public Health
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