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Mechanisms in Myeloid Tumorigenesis 1988
Workshop at the National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, March 22, 1988
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I. Classification of myeloid tumors.- The Pathology of Murine Myelogenous Leukemias.- II. Specific Chromosomal Abnormalities in Human and Murine Myeloid Hematologic Malignancies.- Chromosomal Abnormalities in Myeloid Hematologic Malignancies.- Radiation Induced Deletion of Chromosome 2 in Myeloid Leukemogenesis.- III. Disruption of “Oncogenes” by Virus Insertion in Murine Myeloid Tumorigenesis.- Recombinant Inbred Mouse Strains: Models for Studying the Molecular Genetic Basis of Myeloid Tumorigenesis.- Mechanisms in the Transformation of IL3-Dependent Hematopoietic Stem Cells.- Alternate Forms of MYB: Consequences of virus insertion in myeloid tumorigenesis and alternative splicing in normal development.- IV. Myeloid Leukemogensis Induced by Acute Transforming Virus Constructs in In Vitro and In Vivo Model Systems.- Retrovirus-induced Tumors Whose Developemnt is Facilitiated by a Chronic Immune Response: A Comparison of Two Tumors Committed to the Monocytic Lineage.- Studies of Secondary Transforming Events in Murine c-myc Retrovirus-Induced Monocyte Tumors.- Analysis of the Leukaemogenic Properties of the bcr-v-abl and GM-CSF Genes Using a New Retroviral Vector.- Biological effects of retroviral transfection of the murine Interleukin-3 gene into FDCP-Mix cells.- Conversion of Factor-Dependent Myeloid Cells to Factor Independence: Autocrine Stimulation is Not Coincident with Tumorigenicity.- V. Specific Genes Involved in Myeloid Tumorigenesis.- Biosynthesis of Macrophage Colony-Stimulating Factor (CSF-1): Differential Processing of CSF-1 Precursors Suggests Alternative Mechanisms for Stimulating CSF-1 Receptors.- The ets Family of Genes: Molecular Biology & Functional Implications.- VI. Proposed Mechanisms in Myeloid Tumorigenesis.- Adhesive Defects in Chronic Myeloid Leukaemia.- Induction of Leukemia by Avian Myeloblastosis Virus: A Mechanistic Hypothesis.- Role of Biologic Response Modifiers in the Growth and Differentiation of Myeloid Leukemic Cells.


ISBN-13: 9783642746253
Publisher: Springer (Springer Berlin Heidelberg)
Publication date: December, 2011
Pages: 188
Weight: 334g
Availability: POD
Subcategories: Haematology, Immunology, Oncology
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