(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
Many bacteria, such as certain Neisseria and Haemophilus or Escherichia coli, are able to withstand the bactericidal activity of complement and phagocytes. This bacterial self protection is brought about by encapsulation. Bacterial capsules thus enable the pathogenic bacteria to survive in the host by counter action or evasion of the nonspecific host defense in the early pre immune phase of an infection. It is only in the late immune phase of the infection, when specific anticapsular antibodies are formed and enforce the host's defense system, that this protective action is overcome. Encapsulated bacteria are then killed and eliminated. Interestingly, some capsules can not or only inefficiently be handled by the immune system. The ensuing lack of antibody formation results in a prolonged susceptibility of the host to the pathogenic bacteria exhibiting such capsules. It was found that bacterial capsules consist of acidic poly saccharides. From this it followed that the role of the capsules in the interaction of encapsulated bacteria with the host may be due to the chemistry of the capsular polysaccharides. This led to intensive studies of capsular polysaccharides in many laboratories. Our increasing knowledge of the structural features of capsular polysaccharides prompted not only immuno chemical studies analyzing the interactions of these poly saccharide antigens and characterizing the epitopes, but also investigations into their biosynthesis. These studies were complemented and supported by genetic analyses. Today many interdisciplinary investigations of capsular polysaccharides are in progress.
Contents:
Genetics of Capsular Polysaccharide Production in Bacteria.- Structure and Biosynthesis of the Capsular Antigens of Escherichia coli.- The Serology of Capsular Antigens.- The Role of Bacterial Polysaccharide Capsules as Virulence Factors.- The Biologic Significance of Bacterial Encapsulation.- Capsular Polysaccharides as Vaccine Candidates.- Visualization of the Bacterial Polysaccharide Capsule.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: December, 2011
Pages: 171
Weight: 313g
Availability: Available
Subcategories: Biochemistry, Diseases and Disorders, Immunology, Microbiology
From the same series
Eric Vivier
Kevin V. Morris
Esteban Domingo
Eric Vivier
Tomohiro Kurosaki
Christian Munz
Christian Munz
Michael G. Katze
Bryan R. Cullen
David S. Goodsell
G. Singh Chhatwal
Ralf Bartenschlager
Ellen Heber-Katz
Andreas Rummel
Juan J. Lafaille
Thomas E. Shenk
Ben Adler
Michael B. A. Oldstone
Friedrich Koch-Nolte
Marco Falasca
Michael B. A. Oldstone
Benhur Lee
Freddy Radtke
Klaus Aktories
Jean Langhorne
Michael B. A. Oldstone
Jeremy Nuttall
Robert N. Eisenman
Z F Fu
Peter K. Vogt
Tatsuji Nomura
Wilfried Ellmeier
Marc Daeron
H. Koprowski
Hilary Koprowski
Simon Fillatreau
G. Balakrish Nair
Harris G. Fienberg
Michael B. A. Oldstone
R.M.E. Parkhouse
Lars B. Olding
Charles L. Sawyers
Cornelis Murre
Nicholas Mantis
Pamela A. Kozlowski
Charles E. Samuel
Larry J. Anderson
Kenneth Palmer
Marcel B.M. Teunissen
Rudolf Valenta
M.B.A. Oldstone
Thomas Boehm
Cesare Montecucco
Michael B.A. Oldstone
Hubert Hilbi
Hilary Koprowski
Hung Y. Fan
Walter Doerfler
Polly Roy
Michael Karin
Bryan R. Cullen
Glenn Dranoff
Rafi Ahmed
Jurgen A.. Richt
Ulrich Dobrindt
Ellen Heber-Katz
G. Singh Chhatwal
Ralf Bartenschlager
Peter K. Vogt
Robert L. Coffman
Michael G. Katze
Harald Stenmark
Andreas Rummel
Christian Rommel
Fritz Melchers
H. Koprowski
Didier Trono
Uwe Gross
Christian Rommel
M. Celeste Simon
John E. Johnson
K. Takada
Ellen Heber-Katz
C. Schmaljohn
Axel Rethwilm
Jerry L. Workman
Louis B. Justement
Marco Falasca
P.K. Vogt
Michael N. Hall
M.B.A. Oldstone
K. Hirai
Eric Vivier
Allison Abendroth
Oystein Bruserud
Carolyn Wilson
Freddy Radtke
Benhur Lee
Klaus Aktories
Harald Zur Hausen
J.S. Mackenzie
Adrienne E. Clarke
Stefan H.E. Kaufmann
Bernhard Fleischer
Michael Potter
H. Koprowski
H. Koprowski
Rolf Jessberger
Charles L. Sawyers
Chihiro Sasakawa
Vojo Deretic
Alan L. Rothman
Marco Colonna
H. Koprowski
Karl Maramorosch
H. Koprowski
Eckhard R. Podack
Paul Spearman
Takashi Saito
H. Koprowski
W. Doerfler
Michael Loos
H. Koprowski
Daniel Kolakofsky
H. Koprowski
H. Koprowski
Michael Potter
Kenneth I. Berns
H. Koprowski
J. Lindsay Whitton
Fritz Melchers
Nicholas Mantis
Cornelis Murre
Pamela Kozlowski
Klaus Aktories
Fritz Melchers
O. Haller
Peter K. Vogt
Norman L. Letvin
Dan R. Littman
Michael Potter
Robert F. Ramig
Gillian M. Griffiths
H. Koprowski
David Gray
T.A. Trautner
Michael B. A. Oldstone
Jiri Mestecky
Richard W. Moyer
Fritz Melchers
Michael B. A. Oldstone
Guido Kroemer
Hilary Koprowski
H. Koprowski
Peter K. Vogt
Bruce W. Chesebro
Charles J. Parker
P.J. Sansonetti
H. Koprowski
Rolf Knippers
Walter Doerfler
Virginia L. Miller
Marie H. Kosco-Vilbois
Peggy J. Farnham
Peter M Schlag
Thomas M. Shinnick
Hilary Koprowski
Anthony J. Pawson
Walter Doerfler
Peter K. Vogt
Klaus Jann
Vincent R. Racaniello
Nicholas Muzyczka
Mark Bothwell
Volker Ter Meulen
Jean-Pierre Kraehenbuhl
Michael B. A. Oldstone
P.H. Hofschneider
Steinunn Baekkeskov
H. Koprowski
F. Melchers
Garnett Kelsoe
Arthur E. Frankel
Michael B. A. Oldstone
Michael B. A. Oldstone
Peter Sarnow
Hermann Wagner
Rudolf Rott
H.L. Robinson
Fritz Melchers
John J. Holland
Jeffrey L. Dangl
Richard W. Compans
Charles Mackay
Beat A. Imhof
H. Koprowski
P.K. Vogt
H. Koprowski
P.A. Bachmann
P.K. Vogt
W. Doerfler
H. Koprowski
P.K. Vogt
Leslie Hudson
Michael Potter
Fritz Melchers
Michael B. A. Oldstone
William S. Mason
Peter K. Vogt
H. Koprowski
P.K. Vogt
Melvin J. Bosma
James K. McDougall
Stefan H.E. Kaufmann
N.J. Dimmock
Peter K. Vogt
Michael B. A. Oldstone
Walter Orenstein
Hans-Georg Krausslich
Fritz Melchers
Christa E. Muller-Sieburg
John D. Lambris
Siamon Gordon
Hermann Wagner
H. Koprowski
Hilary Koprowski
D.B. Willis
Walter Doerfler
A. J. Shatkin
P.K. Vogt
Christopher J. Paige
Michael Potter
Michael B. A. Oldstone
W. Doerfler
Henry C. Wu
Hermann Wagner
Michael B. A. Oldstone
H. Koprowski
H. Koprowski
H. Koprowski
H. Koprowski
Barry T. Rouse
H. Koprowski
Fritz Melchers
H. Koprowski
H. Koprowski
H. Koprowski
H. Koprowski
Charles E. Samuel
F. Melchers
H. Koprowski
H. Koprowski
H. Koprowski
Hans-Dieter Klenk
David W. Weiss
U.H. Koszinowski
Ernst-L. Winnacker
Steven Tracy
L. Du Pasquier
Michael B. Kastan
H. Wagner
Fritz Melchers
Ursula Gunthert
T. Ulf Westblom
P.K. Vogt
Lena Claesson-Welsh
C.H. Hagedorn
Stanley B. Prusiner
Wolfgang Baumeister
Bruce Beutler
Louis B. Justement
Ursula Gunthert
Marcel B.M. Teunissen
Rudolf Valenta
Michael Karin
Glenn Dranoff
Rafi Ahmed
Inger Helene Madshus
Lyubomir T. Vassilev
Martin L. Privalsky
Walter Doerfler
Alexander Steinkasserer
Dennis R. Burton
T.M. Koehler
Jurgen A.. Richt
Walter Doerfler
David A. Harris
Yoshihiro Kawaoka
Paula M. Pitha
Branch D. Moody
Scott Dessain
James L. van Etten
Michael B. A. Oldstone
Tony Romeo
Rafi Ahmed
Steven Tracy
Harald Zur Hausen
Michael B. A. Oldstone
Thomas E. Lane
Tasuku Honjo
Marianne Manchester
Walter Doerfler
Diane E. Griffin
Mark Marsh
Alexander V. Karasev
Dorian McGavern
B. W. J. Mahy
Riccardo Dalla-Favera
Sanjeev Krishna
Patrice Boquet
Klaus Aktories
Luis Enjuanes
Christian Rommel
Christian Rommel
M. Celeste Simon
John E. Johnson
Oystein Bruserud
Allison Abendroth
Peter E. Lipsky
Walter Doerfler
Stanley A. Plotkin
John L. Casey
William M. Shafer
Esteban Domingo
Eric Vivier
Takashi Saito
Paul Spearman
Chihiro Sasakawa
Alan L. Rothman
Vojo Deretic
Walter Orenstein
Dorian McGavern
Alexander V. Karasev
Harald Zur Hausen
Michael B. A. Oldstone
Michael B. A. Oldstone
James L. van Etten
Marianne Manchester
Thomas E. Shenk
Tatsuji Nomura
Tony Romeo
Steven Tracy
Peter K. Vogt
Scott Dessain
Paula M. Pitha
D.B. Moody
Peter K. Vogt
Robert A. Weiss
Rafi Ahmed
Stanley A. Plotkin
Tasuku Honjo
Walter Doerfler
William M. Shafer
John L. Casey
Peter E. Lipsky
Thomas E. Lane
Robert N. Eisenman