BOOKS BY CATEGORY
Your Account
Acute Promyelitic Leukemia
Molecular Genetics, Mouse Models and Targeted Therapy
Price
Quantity
£180.00
(To see other currencies, click on price)
Hardback
Add to basket  

MORE ABOUT THIS BOOK

Main description:

Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research  that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development  of targeted therapy.


Back cover:

(will follow)


Contents:

APL as a paradigm in biomedical research: a journey towards the cure.- SUMO, the three Rs and cancer.- Arsenic Trioxide and APL: clinical and biological.- Treatment of APL by retinoids.- The PLZF gene of t(11;17)-associated APL.- Front line clinical trials and minimal residual disease monitoring in APL.- Targeting APL fusion proteins by peptide interference.- Emerging role for microRNAs in APL.- The design of selective and non-selective combination therapy for APL.- Histone deacetylase inhibitors in APL and beyond.- Monoclonal antibody therapy of APL.- Mouse Models of Acute Promyelocytic Leukemia.- Subject index


PRODUCT DETAILS

ISBN-13: 9783540345923
Publisher: Springer (Springer Berlin Heidelberg)
Publication date: December, 2006
Pages: 282
Weight: 649g
Availability: POD
Subcategories: General Issues, Genetics, Oncology
Related books
From the same series

CUSTOMER REVIEWS

Average Rating