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MORE ABOUT THIS BOOK
Main description:
The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies. The second part comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented.
Contents:
Preclinical Part.- Biological Basis of Combined Radio- and Chemotherapy.- Combinations of Antimetabolites and Ionizing Radiation.- Combinations of Taxanes and Ionizing Radiation.- Combinations of Topoisomerase Inhibitors and Ionizing Radiation.- Combinations of Hypoxia-Targeting Compounds and Radiation-Activated Prodrugs with Ionizing Radiation.- Combinations of Platinum Compounds and Ionizing Radiation.- Combinations of Cytotoxic Drugs, Ionizing Radiation, and Angiogenesis Inhibitors.- Combinations of Cytotoxic Drugs, Ionizing Radiation and EGFR Inhibitors.- Combinations of Cytotoxic Drugs, Ionizing Radiation, and Mammalian Target of Rapamycin (mTOR) Inhibitors.- Combinations of Ionizing Radiation and Other Sensitizing Agents.- Radiotherapy and Tumor-Targeted Drug Delivery.- Clinical Part.- Applications in Malignant Brain Tumors.- Applications in Head and Neck Cancer.- Applications in Esophageal and Gastric Cancer.- Novel Chemoradiation in Localized Pancreatic Cancer: Clinical Studies.- Applications in Lung Cancer.- Integration of Radiation Therapy and Systemic Therapy for Breast Cancer.- Applications in Rectal and Anal Cancer.- Concomitant Radiation and Chemotherapy in Muscle-Invasive Bladder Cancer.- Applications to Gynecological Cancers.- Early and Late Treatment-Induced Toxicity.- Feasibility of Combined Chemo- and Radiation Treatment in Elderly/Comorbid Patients.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: February, 2010
Pages: 362
Weight: 896g
Availability: Available
Subcategories: Biochemistry, General, Oncology, Radiology, Respiratory Medicine
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