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Modification of Radiation Response
Cytokines, Growth Factors, and Other Biological Targets
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Main description:

This book describes and summarizes the radiation responses of both normal and neoplastic tissues with a focus on rational strategies for the modification of these responses. Emerging data from molecular oncology and radiobiology are reviewed in depth. The book covers not only general principles of radiation-induced reactions but also a large number of preclinical and clinical data that will guide the reader through this complex and dynamic field and will provide valuable information for the development of further research projects.


Contents:

Normal Tissues: Role of Radiation-Induced Signaling Proteins in the Response of Repopulating Normal Tissues (K.-R. Trott); Role of Radiation-Induced Signaling Proteins in the Response of Vascular and Connective Tissues (H.-P. Rodemann); Pathogenetic Mechanisms of Lung Fibrosis (W. Doerr et al.); Strategies for Modification of the Radiation Response of the Lung (E.L. Travis); Strategies for Modification of the Radiation Response of Gastrointestinal Organs (M. Hauer-Jensen); Mechanisms and Modification of the Radiation Response of the CNS; Haematopoetic Tissue I: Response Modification by EPO (J. Dunst); Haematopoetic Tissue II: Role of Colony-Stimulating Factors (G. Wagemaker); Oral Mucosa: Response Modification by Keratinocyte Growth Factor (W. Doerr); Malignancies: Role of Growth Factors in Tumor Growth and Progression (incl. GYN Tumors) (A. W. Fyles); CNS Tumors (C. Nieder/J. Schlegel); Lung, Head and Neck, GI Tumors (G. Stuben/ M. Stuschke); Role of Signalling Pathway Modification (O. Riesterer/S. Bodis); Anti-VEGT Strategies plus Radiotherapy (D. Zips/M. Baumann); Anti-EGFR Strategies plus Radiotherapy (L. Milas); Enhancement of the Radiation Response with Interleukins/Interferons (F. Lohr); Enhancement of the Radiation Response with TNF/TRAIL (R.E. Meyn); Enhancement of the Radiation Responses with COX-2 Inhibitors (L. Milas/K. Kian Ang); Enhancement of the Radiation Response with Farnesyltransferase Inhibitors (E.J. Bernhard et al.); Subject Index. List of Contributors.


PRODUCT DETAILS

ISBN-13: 9783642626708
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: October, 2012
Pages: 284
Weight: 649g
Availability: Available
Subcategories: Oncology, Radiology
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