Main description:

Genetic testing has become commonplace, and clinicians are frequently able to use knowledge of an individual's specific genetic differences to guide their course of action. Molecular Genetics and Personalized Medicine highlights developments that have been made in the field of molecular genetics and how they have been applied clinically. It will serve as a useful reference for physicians hoping to better understand the role of molecular medicine in clinical practice. In addition, it should also prove to be an invaluable resource for the basic scientist that wants to better understand how advances in the laboratory are being moved from the bench to the bedside.

All chapters are written by experts in their fields and include the most up to date medical information. The authors simplify complex genetic concepts and focus on practical patient related issues. The book will be of great value to pathologists, hematologists/oncologists, clinical geneticists, high-risk obstetricians, general practitioners, and physicians in all other medical specialties who utilize genetic testing to direct therapy.

Contents:

01. Molecular Genetic Testing in the Genomic Era
Charles Sailey and Ferrin Wheeler

02. Array Comparative Genomic Hybridization in Cytogenetics and Molecular Genetics
S. Hussain Askree and Madhuri Hegde

03. Pharmacogenomics: Tailoring Treatment Based on Genotype
Alan H.B. Wu

04. Somatic Alterations and Targeted Therapy
Allison M. Cushman-Vokoun

05. Genome Wide Association Studies in Disease Risk Calculation: The Role of Bioinformatics in Patient Care
Todd L. Edwards, Digna R. Velez Edwards, Marylyn D. Ritchie

06. Presymptomatic Genetic Testing: Shifting the Emphasis from Reaction to Prevention
Irene H. Hung, John C. Carey

07. Prenatal Testing: Screening, Diagnosis and Preimplantation Genetic Diagnosis
Eugene Pergament

08. Newborn Screening for Metabolic Disorders
Marzia Pasquali and Nicola Longo

09. The Role of Genetic Counseling in Everyday Medical Practice
Kimberly J. Hart, Erin E. Baldwin, and D. Hunter Best

10. Direct-to-Consumer Genetic Testing
Caroline F. Wright and Daniel G. MacArthur