(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
There has been an explosion of research activity related to angiogenesis in recent years, and hundreds of laboratories worldwide are actively involved in many aspects of angiogenesiS. The literature on angiogenesis increases exponentially every year, and more than 16,000 peer-reviewed articles have been published the past 25 years, which are scattered in basic science and clinical journals. The complexity of the cascade of events leading to new vessel formation from preexisting ones has challenged scientists in cell biology, biochemistry, physiology, pharmacology, molecular biology, developmental biology, and other fields. With their multidisciplinary approach and the powerful new techniques that have been developed, the progress in understanding angiogenesis has been impressive indeed. Only 12 years ago the mention of an angiogenic factor caused skepticism. Today we have the complete amino-acid fiequence and their genes cloned for at least 9 angiogenic factors. Many laboratories are studying their role in angiogenesis, and several biotechnology firms have a keen interest in commercial developments relative to these molecules. The role of extracellular matrix components in angiogenesis and the interaction of endothelial cells with other cell types such as pericytes, smooth muscle cells, and inflammatory cells have been studied by other groups. This rapid expansion is the result of a realization that in many disease states a common underlying pathology is a derangement in angiogenesis.
Contents:
Heterogeneity of Endothelial Cells: On the Possible Role of Endothelial Cell Heterogeneity in Angiogenesis; P.I. Lelkes, et al. Role of Extracellular Matrix in Angiogenesis: Plasminogen Activators in Fibrinolysis and Pericellular Proteolysis. Studies on Human Endothelial Cells in vitro; V.W.M. van Hinsbergh, et al. Angiogenic Factors and Their Receptors: Basic Fibroblast Growth Factor Expression in Endothelial Cells: An Autocrine Role in Angiogenesis? A. Gualandris, et al. The Biology of Vascular Endothelial Growth Factor; N. Ferrara. Physiological Angiogenesis: Angiogenesis in the Female Reproductive Organs; L.P. Reynolds, et al. Pathological Angiogenesis: Tumor Oxygenation and Tumor Vascularity: Evidence for Their Clinical Relevance in Cancer of the Uterine Cervix and Considerations on Their Potential Biological Role in Tumor Progression; M. Hoeckel, et al. Inhibitors of Angiogenesis: A Heparanaseinhibitory, bFGFbinding Sulfated Oligosaccharide That Inhibits Angiogenesis ex ovo Has Potent Antitumor and Antimetastatic Activity in vivo; R.J. Tressler, et al. Biotechnological Aspects of Angiogenesis: A Method for the in vivo Quantitation of Angiogenesis in the Rabbit Corneal Model; R.W. Shaffer, M. Friedlander. 13 additional articles. Index.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: October, 2011
Pages: 312
Weight: 542g
Availability: Available
Subcategories: Biochemistry, Pharmacology
From the same series
Holger Schmid-Schonbein
C. David
Athel Cornish-Bowden
Roy H. Pottier
A Cooper
W. Taylor
Gregory Gregoriadis
Robert A. Samson
A. Pecile
Nikolas Zagris
Peter A.V. Anderson
Allan D. Callow
S.S. Davis
Gregory Gregoriadis
Kalliopi A. Roubelakis-Angelakis
F. Cattabeni
Janice S. Dorman
C. Nicolini
Ruth Bellairs
Curtis C. Travis
David L. Hawksworth
Bengt Samuelsson
Thomas Elbert
Athel Cornish-Bowden
Allan D. Callow
F. Delange
Giorgio M. Innocenti
W.C. McCallum
John Alden
Douglas R.O. Morrison
B. Marin
Brian L. Strom
Gregory Gregoriadis
M.I. Mackness
Erik De Clercq
Wilfred Cote
J. Axelrod
Jacques Dumont
Antonio Borsellino
G. Gregoriadis
Claudio Nicolini
Martino Grandolfo
Antonio Pecile
F. Lamberti
Terry J. Beveridge
Michael E. Maragoudakis
Cesare Sirtori
Curtis Travis
Shimon Gatt
Hans Degn
E.C. Tjamos
Michael E. Maragoudakis
Claudio Nicolini
P. H. Smith
M. Ali
A. Quintanilha
Jose Cunha-Vaz
C Thomas Caskey
J. E. Celis
Alan Kolber
Gurdal N. Alaeddinoglu
R. Bercoff
Stephane Swillens
J. Don Read
H. F. Bradford
Francesco Ghetti
P.M. Mannucci
Suresh C. Srivastava
John S. Axford
Frederic J. Burns
Paul F. Lurquin
Giorgio M. Innocenti
Lester Packer
Filipe Cabello
William F. Dove
F. Berti
Hubert Peeters
Claudio Nicolini
Prakash Chandra
Gregory Gregoriadis
Gregory Gregoriadis
Corrado L. Galli
Erik De Clercq
Demetrios A. Spandidos
Claudio Nicolini
H. Peeters
M. L. Thakur
R. T. Walker
Corraldo Galli
Claudio Nicolini
Robert M. Burton
Hans-Jurg Marthy
R. E. Foreman
Joan H. Argyroudi-Akoyunoglou
Miral Dizdaroglu
Francisco Rodriguez-Valera
Russel J. Reiter
Giulio Milazzo
Constantine Zervos
Arne Valberg
Allan D. Callow
J.Richard Hinchliffe
R.G. Herrmann
Nahum Sonenberg
P.J. Barnes
Franco Celada
Joseph G. Cloud
Gregory Gregoriadis
Gregory Gregoriadis
Sarnoff A. Mednick
Simon D. Shorvon
Oleg Jardetzky
Vincent Torre
J. Martin-Comin
Leo M. Chalupa
Michael E. Maragoudakis
Sarnoff A. Mednick
Gregory Gregoriadis
P. Bagnoli
E.M. Fielden
David B. Allison
Russel J. Reiter
Harry Meinardi
D.J. Galton
Gregory Gregoriadis
Jacques Breton
Richard Bandler
Andrea Boicelli
Wolfram Boucsein
Nuri Akkas
Sadis Matalon
William M. Wardell
D. Karcher
F. Berti
Lucien Ledoux
Barry W. Festoff
Claudio Nicolini
Orio Ciferri
R. Perez-Bercoff
A. Breccia
F. Hillenkamp
Rodolfo Paoletti
Robert W Wissler
R. D. Freeman
L.M.G. Heilmeyer
Ralph Bradshaw
F. Delange
B. Samuelson
G. Galli
Tom Scott
Gregory Gregoriadis
Aldo Rescigno
M.R. Ahuja
Frade Fonnum
Vincent Torre
Miguel A. Merchán
T. Norman Palmer
Gregory Gregoriadis
Robert C. Brown
Upendra K. Pandit
E. Kenneth Weir
H. Hildebrand
Allan D. Callow
M. Paubert-Braquet
Giuliano Colombetti
Corrado L. Galli
John Stein
Ruth F. Jarrett
Gregory Gregoriadis
Ned H.C. Hwang