(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
This volume presents lecture notes from the session of the International School of Pharmacology, at the "Ettore Majorana" Centre, on Advances in Prostaglandins that took place in Erice (Sicily), October 4 to October 15, 1976. The School was a NATO Advanced Study Institute. The aim of this international course was a compre- hensive discussion by experts in various disciplines of the present status of our knowledge of the biological role of prostaglandins and thromboxanes. The synthesis, metabolism, and function of prosta- glandins have been evaluated at the cellular level, in isolated tissues, and/or in the intact organism. The mode of action of prostaglandins and their interactions, particularly with cyclic nucleotides, in normal and pathological conditions, has been discussed with the aim of understanding the possible role of these compounds in hormonal regulation and cell response. The prostaglandin biosynthetic capacity of different tissues, under various experimental conditions, in the presence of specific precursors, and the inhibitory ac- tivity of different agents have been examined to ascer- tain the relationship between function and metabolism.
For these reasons the discussion has also been extended to the methods (biological, immunological, and spectrometric) available for the direct and specific determination of prostaglandins and the evaluation of their synthesis and metabolism. The Editors hope that the book will be useful both to beginners and to those with a long-time interest in prostaglandins. F. Berti B. Samuelsson G. P. Velo v CONTENTS Chemistry of Prostaglandins and Thromboxanes . .
Contents:
Chemistry of Prostaglandins and Thromboxanes.- Some Synthetic Aspects of Prostaglandins.- Prostaglandin Bioassay.- Radioimmunoassays of Prostaglandins and Thromboxanes.- Vapor-Phase Methods for Quantitative Evaluation of Prostaglandins and Related Compounds in Biological Samples.- Biosynthesis of Prostaglandins.- Metabolism of Prostaglandins.- Screening for Inhibitors of Prostaglandin and Thromboxane Biosynthesis.- Prostaglandin Synthetase Inhibitors.- Respiratory System (General Introduction).- Generation of Prostaglandin and Thromboxane-like Substances by Large Airways and Lung Parenchyma.- Clinical Effects of the Prostaglandins on the Respiratory System.- Aspirin-Sensitive Asthma: Its Relationship to Inhibition of Prostaglandin Biosynthesis.- Physiological Roles of Prostaglandins in Reproduction.- Clinical Use of Prostaglandins for Termination of Pregnancy and Induction of Labour.- to Circulatory System.- Polypeptides: Vascular Actions as Modified by Prostaglandins.- Prostaglandins and Vascular Wall.- The Role of Prostaglandins in Gastrointestinal Tone and Motility.- Effect of Prostaglandins on Gastrointestinal Functions.- Antisecretory Prostaglandins and Gastric Mucosal Erosions in the Rat.- The Role of Prostaglandins and Cyclic Nucleotides in Inflammation.- Prostaglandins and Mast Cell Histamine Release.- Prostaglandins and Non-Steroidal Anti-Inflammatory Drugs.- Influence of Anti-Inflammatory Steroids on Prostaglandin and Thromboxane Release from Tissues.- Influence of Prostaglandins on Central Functions.- Prostaglandins as Modulators of Autonomic Neuroeffector Transmission.- Inflammatory Pain and Fever.- List of Contributors.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: December, 2012
Pages: 449
Weight: 868g
Availability: Available
Subcategories: Biochemistry
From the same series
Holger Schmid-Schonbein
C. David
Athel Cornish-Bowden
Roy H. Pottier
A Cooper
W. Taylor
Gregory Gregoriadis
Robert A. Samson
A. Pecile
Nikolas Zagris
Peter A.V. Anderson
Allan D. Callow
S.S. Davis
Gregory Gregoriadis
Kalliopi A. Roubelakis-Angelakis
F. Cattabeni
Janice S. Dorman
C. Nicolini
Ruth Bellairs
Curtis C. Travis
David L. Hawksworth
Bengt Samuelsson
Thomas Elbert
Athel Cornish-Bowden
Allan D. Callow
F. Delange
Giorgio M. Innocenti
W.C. McCallum
John Alden
Douglas R.O. Morrison
B. Marin
Brian L. Strom
Gregory Gregoriadis
M.I. Mackness
Erik De Clercq
Wilfred Cote
J. Axelrod
Jacques Dumont
Antonio Borsellino
G. Gregoriadis
Claudio Nicolini
Martino Grandolfo
Antonio Pecile
F. Lamberti
Terry J. Beveridge
Michael E. Maragoudakis
Cesare Sirtori
Curtis Travis
Shimon Gatt
Hans Degn
E.C. Tjamos
Michael E. Maragoudakis
Claudio Nicolini
P. H. Smith
M. Ali
A. Quintanilha
Jose Cunha-Vaz
C Thomas Caskey
J. E. Celis
Alan Kolber
Gurdal N. Alaeddinoglu
R. Bercoff
Stephane Swillens
J. Don Read
H. F. Bradford
Francesco Ghetti
P.M. Mannucci
Suresh C. Srivastava
John S. Axford
Frederic J. Burns
Paul F. Lurquin
Giorgio M. Innocenti
Lester Packer
Filipe Cabello
William F. Dove
Hubert Peeters
Claudio Nicolini
Prakash Chandra
Gregory Gregoriadis
Gregory Gregoriadis
Corrado L. Galli
Erik De Clercq
Demetrios A. Spandidos
Claudio Nicolini
H. Peeters
M. L. Thakur
R. T. Walker
Corraldo Galli
Claudio Nicolini
Robert M. Burton
Hans-Jurg Marthy
R. E. Foreman
Joan H. Argyroudi-Akoyunoglou
Miral Dizdaroglu
Francisco Rodriguez-Valera
Russel J. Reiter
Giulio Milazzo
Constantine Zervos
Arne Valberg
Allan D. Callow
J.Richard Hinchliffe
R.G. Herrmann
Nahum Sonenberg
P.J. Barnes
Franco Celada
Joseph G. Cloud
Gregory Gregoriadis
Gregory Gregoriadis
Sarnoff A. Mednick
Simon D. Shorvon
Oleg Jardetzky
Vincent Torre
J. Martin-Comin
Leo M. Chalupa
Michael E. Maragoudakis
Sarnoff A. Mednick
Gregory Gregoriadis
P. Bagnoli
E.M. Fielden
David B. Allison
Russel J. Reiter
Harry Meinardi
D.J. Galton
Gregory Gregoriadis
Jacques Breton
Richard Bandler
Andrea Boicelli
Wolfram Boucsein
Nuri Akkas
Sadis Matalon
William M. Wardell
D. Karcher
F. Berti
Lucien Ledoux
Barry W. Festoff
Claudio Nicolini
Orio Ciferri
R. Perez-Bercoff
A. Breccia
F. Hillenkamp
Rodolfo Paoletti
Robert W Wissler
R. D. Freeman
L.M.G. Heilmeyer
Ralph Bradshaw
F. Delange
B. Samuelson
G. Galli
Tom Scott
Gregory Gregoriadis
Aldo Rescigno
M.R. Ahuja
Frade Fonnum
Vincent Torre
Miguel A. Merchán
T. Norman Palmer
Gregory Gregoriadis
Robert C. Brown
Upendra K. Pandit
E. Kenneth Weir
H. Hildebrand
Allan D. Callow
M. Paubert-Braquet
Michael E. Maragoudakis
Giuliano Colombetti
Corrado L. Galli
John Stein
Ruth F. Jarrett
Gregory Gregoriadis
Ned H.C. Hwang