BOOKS BY CATEGORY
Your Account
Current Topics in Microbiology and Immunology
Price
Quantity
£94.50
(To see other currencies, click on price)
Paperback / softback
Add to basket  

MORE ABOUT THIS BOOK

Main description:

1.1 Classification of Togaviruses The family, Togaviridae, is composed of the alphaviruses, the flaviviruses, rubella (a rubivirus), and the pestiviruses (Fenner, 1976). Of these four genera, two (the alpha- and flaviviruses) are transmitted by blood-sucking arthropods, specif­ ically mosquitoes and ticks. Among the togaviruses, extensive studies of defective interfering (DI) particles have so far been carried out only with Sindbis virus (SV) and Semliki Forest virus (SFV), both members of the alphavirus genus. Since these viruses are so similar, in most cases it will be assumed that what is true of one is also true of the other. 1.2 Definition of Defective Interfering (DI) Particles Defective interfering viral particles, as defined by Huang (1973), have the follow­ ing properties: (1) they are deletion mutants and therefore lack large amounts of the genetic material present in the standard virus; (2) they contain the same viral structural proteins as standard virus; (3) they are unable to replicate alone; however, they are replicated in cells co-infected with standard virions; and (4) at the same time as they require standard virus to replicate, they inhibit the replication of standard virus and hence are interfering.


Contents:

Genetic Potential of Bunyaviruses.- Defective Interfering Particles of Togaviruses.- The Fv-1 Gene of the Mouse and its Control of Murine Leukemia Virus Replication.- Defective Interfering Particles of Rhabdoviruses.- Indexed in Current Contents.


PRODUCT DETAILS

ISBN-13: 9783642673436
Publisher: Springer (Springer Berlin Heidelberg)
Publication date: November, 2011
Pages: 180
Weight: 321g
Availability: POD
Subcategories: General Issues, General Practice
Related books
From the same series

CUSTOMER REVIEWS

Average Rating