In the United States in 1997, 28800 new cases of malignant tumors of the kidney and renal pelvis were diagnosed along with 2100 new cases of malignant tumors of the ureter and other urinary organs, 7200 primary malignant tumors of the testis, and 1300 primary malignant tumors of the penis and other genital organs. In large measure, surgery is the treatment of choice for these tumors, but radiation therapy is in creasingly recognized as having significant and important curative and palliative bene fits in each of these tumor sites. Surgery is the standard form of treatment for non metastatic renal cell carcinomas as well as for malignancies of the renal pelvis and ureter, with radical nephrectomy and radical uretectomy being employed. However, postoperative radiation therapy is of value for those patients who demonstrate evi dence of residual tumor following surgery, transection of tumor during surgery, or positive regional lymph node drainage. As regards the rare tumors that involve the female urethra, surgical resection is appropriate for those that are limited and local in character and amenable to partial ureterectomy. With tumors that are more advanced in character, however, local recurrence and lymphatic dissemination are significant problems, and treatmentby radiation therapy programs alone yield satisfactory control rates as well as limited recurrences and long-term survivors. For primary tumors involving the testis, the major approach to nonseminomatous tumors is surgical resection with postsurgical systemic chemotherapy.
- the book provides current information on the etiology, diagnosis and treatment - well referenced, comprehensive update on the topics presented - provides good assistance to teaching - numerous illustrations assist the reader in obtaining a better understanding of the presented data
This book provides readers with current information on the etiology, diagnosis, and treatment of carcinomas of the kidney and testis, as well as several less common tumors of the genitourinary tract. Recent contributions in epidemiology and molecular genetics are discussed with a view to their importance for clinical practice. Novel approaches to the treatment of several important tumors are presented, with emphasis on multidisciplinary patient management. The numerous illustrations will assist the reader in obtaining a better understanding of the presented data.
Renal Cell Carcinoma.- 1 Epidemiology of Renal Cell Carcinoma.- 2 Pathology of Renal Cell Carcinoma.- 3 Genetics of Renal Cell Carcinoma.- 4 Imaging of Renal Parenchymal Tumors.- 5 Radical Nephrectomy.- 6 Nephron-Sparing Surgery.- 7 Palliative Surgical Therapy.- 8 Preoperative and Palliative Embolization.- 9 Immunotherapy and Chemotherapy for Metastatic Renal Cell Carcinoma.- 10 The Role of Radiotherapy in the Management of Patients with Renal Cell Carcinoma.- 11 Radiation Therapy for Carcinoma of the Renal Pelvis and Ureters.- 12 Diagnosis and Management of Tumors of the Adrenal Gland.- 13 Surgical Treatment of Adrenal Gland Tumors.- 14 Diagnosis and Management of Retroperitoneal Tumors in Pediatric Patients.- Carcinoma of the Testis CAR.- 15 Carcinoma of the Testis: The Epidemiology and Etiology.- 16 Carcinoma of the Testis: Pathology.- 17 Imaging of Testicular Neoplasms.- 18 Surgical Treatment for Early Germ Cell Tumors.- 19 Surgery for Advanced Stage Testis Cancer.- 20 Radiotherapy in Early Seminoma.- 21 Radiotherapy for Bulky Seminoma.- 22 Radiotherapy of Testicular Germ Cell Tumors: The German Experience.- 23 Chemotherapy for Seminoma.- 24 Nonseminomatous Germ Cell Tumors.- 25 Is a Policy of Surveillance Warranted in Early Stage Testicular Cancer Following Orchiectomy?.- 26 Fertility Following Treatment of Testicular Carcinoma.- 27 Testicular Tumors in Prepubertal Boys: Assessment and Treatment.- Carcinoma of the Penis and Scrotum.- 28 Surgical Management of Carcinoma of the Penis and Scrotum.- 29 Radiotherapy in Cancer of the Penis, Male Urethra, and Scrotum.- Carcinoma of the Female Urethra.- 30 Urethral Carcinoma of the Female Urethra: Surgical Management.- 31 Radiation Therapy for the Female Urethra.- Sarcoma of the Genito-Urinary Tract in Adults.- 32 Primary Retroperitoneal Sarcomas.- 33 Adult Genitourinary Sarcomas: Pelvic Sarcomas.- 34 Hematologic Malignancies Involving the Genitourinary System.- 35 Rhabdomyosarcoma of the Genitourinary Tract in Pediatric Patients.- 36 Measures to Optimize Quality of Life in Patients Treated for Genitourinary Tumors.- 37 Racial Differences in the Incidence, Behavior, and Management of Tumors of the Genitourinary Tract.- 38 Risk of Second Malignancies Following Treatment for Genitourinary Tumors.- List of Contributors.