For decades this virus system has served--and continues to do so--to pioneer investigations on the molecular biology, biochemistry and genetics of mammalian cell systems. This three volume work presents an up-to-date account of recent basic research in one of the most important experimental systems for biochemical, cell biological, genetic, virological and epidemiological investigations in mammalian molecular biology. In this, the second of three volumes, the attention is turned to such topics as DNA replication, recombination and integration, and post-transcriptional control. The chapters have been written by an international group of leading experts in their respective fields of interest.
List of Contents.- Adenovirus DNA Replication.- Molecular Interactions During Adenovirus DNA Replication.- Expression, Nuclear Transport, and Phosphorylation of Adenovirus DNA Replication Proteins.- Homologous Recombination in the Replicative Cycle of Adenoviruses and Its Relationship to DNA Replication.- The Mechanism of Adenovirus DNA Integration: Studies in a Cell-Free System.- Post-transcriptional Control of Adenovirus Gene Expression.- Structure, Function, and Evolution of Adenovirus Virus-Associated RNAs.- The Complete Nucleotide Sequence of the DNA of Human Adenovirus Type 12.