Main description:

The Human Hypothalamus: Neuropsychiatric Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume identifies the neurobiology and neurophysiology of disorders relating to the hypothalamus and provides treatment information for these disorders. Disorders covered include neuropsychiatric, neurodegenerative, periodic, and autoimmune disorders. Coverage includes Alzheimer's, Parkinson's, epilepsy, sleep, pain, depression, anxiety, OCD, PTSD, schizophrenia, autism, aggressions, addiction, and more.

Contents:

1. Introduction: The human hypothalamus and neuropsychiatric disorders
SECTION 21 Trauma and iatrogenic disorders
2. Chronic traumatic encephalopathy and the nucleus basalis of Meynert
SECTION 22 Neurobehavioral disorders
3. Hypothalamic stress systems in mood disorders
4. Light therapy for mood disorders
5. Neurobiology of peripartum mental illness
6. The hypothalamo-pituitary-adrenal axis and the autonomic nervous system in burnout
7. Posterior hypothalamus as a target in the treatment of aggression: From lesioning to deep brain stimulation
8. The implications of hypothalamic abnormalities for schizophrenia
9. The promiscuity of the oxytocin-vasopressin systems and their involvement in autism
spectrum disorder
SECTION 23 Epilepsy
10. Gelastic seizures and the hypothalamic hamartoma syndrome: Epileptogenesis beyond the lesion?
11. The interactions between reproductive hormones and epilepsy
SECTION 24 Neurodegenerative disorders
12. Alternative splicing in aging and Alzheimer's disease: Highlighting the role of tau and estrogen receptor a isoforms in the hypothalamus
13. Cholinergic neurodegeneration in Alzheimer disease mouse models
14. Autonomic disorders in Parkinson disease: Disrupted hypothalamic connectivity as revealed from resting-state functional magnetic resonance imaging
15. Hypothalamic a-synuclein and its relation to autonomic symptoms and neuroendocrine abnormalities in Parkinson disease
16. Lewy bodies in the olfactory system and the hypothalamus
17. Hypothalamic pathology in Huntington disease
18. Endocrine dysfunction in adrenoleukodystrophy
19. Hypothalamic symptoms of frontotemporal dementia disorders
SECTION 25 Olfactory system
20. The vomeronasal organ: History, development, morphology, and functional neuroanatomy
21. Pheromone effects on the human hypothalamus in relation to sexual orientation and gender
22. Kallmann syndrome and idiopathic hypogonadotropic hypogonadism: The role of semaphorin signaling on GnRH neurons
23. Olfaction as an early marker of Parkinson's disease and Alzheimer's disease
SECTION 26 Autonomic and sleep disorders
24. The hypothalamus and its role in hypertension
25. The heart is lost without the hypothalamus
26. Sleep disorders and the hypothalamus
SECTION 27 Addiction and pain
27. Molecular genetics of neurotransmitters and neuropeptides involved in Internet use disorders including first insights on a potential role of hypothalamus' oxytocin hormone
28. The neurobiology of cluster headache
SECTION 28 Critical care and brain-death
29. Endocrine interventions in the intensive care unit
30. Hypothalamic function in patients diagnosed as brain dead its practical consequences