(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma. The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data. Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.
Contents:
Preclinical models that illuminate the bone metastasis cascade.- The role of bone microenvironment, vitamin D and calcium.- Bisphosphonates: Prevention of bone metastases in breast cancer.- Bisphosphonates: Prevention of bone metastases in lung cancer.- Bisphosphonates: Prevention of bone metastases in prostate cancer.- Bisphosphonates: Prevention of disease progression in patients with multiple myeloma.- Combinations of bisphosphonates and classical anticancer drugs - a preclinical perspective.- Special issues in the elderly patient.- Denosumab: First data and ongoing studies on the prevention of bone metastases.- Diagnostic and prognostic use of bone turnover markers.- Osteolytic and osteoblastic bone metastases: Two extremes of the same spectrum?.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: January, 2012
Pages: 242
Weight: 535g
Availability: Not available (reason unspecified)
Subcategories: Oncology, Oncology
From the same series
Friedhelm Raue
Thomas Ried
Christian Wittekind
Florian Otto
Markus W. Buchler
C. Stroszczynski
Manfred Dietel
H.-J. Senn
Otmar Schober
Jean-Nicolas Vauthey
Elmar Detering
Richard P. Baum
G. Mathe
R. Gross
Florian Otto
Uwe M. Martens
Michail Ignatiadis
Georges Mathe
M. S. Griem
Jack Cuzick
Michael Gnant
Ute Goerling
Hans-Jorg Senn
Werner H. Kirsten
F.A. Langley
Kuan-Teh Jeang
Janusz Jankowski
J. Bernard
Thomas Moehler
Andrea Tannapfel
S.K. Carter
R. S. Nelson
Kerry S. Courneya
Rolf D. Issels
Hans-Jorg Senn
Florian Otto
W. Fischbach
Umberto Veronesi
Otmar Schober
Paul M. Schneider
Hans-Jorg Senn
Wolfgang Tilgen
Jean-Nicolas Vauthey
Richard P. Baum
J. L. Hayward
W. H. Kirsten
Henry T. Lynch
Georges Mathe
G. T. Pack
Leon Goldman
Charles G. Moertel
R.G. Freeman
L. Manuila
Agnes Glaus
Rudiger Liersch
Richard Schindler
Uwe M. Martens
W.A. Fuchs
Michail Ignatiadis
Edward S. Meek
P. Roy-Burman
Merle Mizell
Jean Lindenmann
Pavel Koldovsky
Enrico Anglesio
Georges Mathe
Hans-Jorg Senn
James H. Goldie
Donald Metcalf
Siegfried Seeber
Israel Penn
B. Sokoloff
Manfred Schwab
E. Grundmann
H.-D. Pape
Robert S. Nelson
G. Mathe
J. Lange
G. Bonadonna
J. Szymendera
H. B. Marsden
K. E. Stanley
E. Grundmann
C. Bohuon
Pierre Denoix
A. C. Templeton
Ekkehard Grundmann
Michael Wannenmacher
Ivan Damjanov
Wolf-Dieter Ludwig
Friedhelm Raue
M. L. Jacobs
H.K. Muller-Hermelink
Rita Engenhart-Cabillic
E. Grundmann
Peter M Schlag
E. Grundmann
Ekkehard Grundmann
G. Mathe
Donald Metcalf
S. Brunner
F. F. Holmes
G. Mathe
G. Mathe
Pierre Band
Stephen C. Schimpff
K. Schwemmle
K. Hoffken
Friedhelm Raue
H. R. Scheurlen
Aron Goldhirsch
H. Acker
Hans-Jorg Senn
F. G. J. Hayhoe
William Duncan
E. Thiel
Hans-Jorg Senn
K. Musshoff
Hans-Jorg Senn
A. Rossi-Fanelli
Peo C. Koller
Volker Diehl
K. Hoffken
H.-J. Senn
Bruce S. Schoenberg
G. St. Arneault
S.K. Carter
B. Henningsen
J. Hekmatpanah
G. Mathe
E. Grundmann
Hans-Jorg Senn
G. Mathe
Sam Brunner
Hans-Jorg Senn
V. Hofmann
Michael Wannenmacher
G. Wagner
Hans-Jorg Senn
Rudolf Pichlmayr
Frank M. Torti
Michael Wannenmacher
William Duncan
G. Mathe
M. Bamberg
H.-P. Lohrmann
E. Grundmann
Niels Neymark
Peter M Schlag
P. Koldovsky
G. Nass
W. Duncan
Ekkehard Grundmann
Richard P. Gallagher
Hans-Jorg Senn
W. Duncan
W. Duncan
S.K. Carter
Michael Molls
Sam Brunner
Peter Boyle
Maurizio Ponz de Leon
U. Reinhold
Gunter Burg
K. Hoffken
H.-J. Senn
F.W. Schildberg
Beat Thurlimann
Janusz Jankowski
Thomas Moehler
Andrea Tannapfel
Kerry S. Courneya
H.-J. Senn
Per-Ulf Tunn
Andreas von Deimling
Antonella Surbone
Ursula Kapp
Hans-Jorg Senn
Santiago Gonzalez-Moreno
Hanno Riess
Paul M. Schneider
Uwe M. Martens
Rudiger Liersch
Renzo Brun del Re
Andreas von Deimling
Ursula Kapp
Per-Ulf Tunn
Hanno Riess
Antonella Surbone
Manfred Dietel
Santiago Gonzalez-Moreno
Louis Denis
H.-J. Senn
C. Stroszczynski