(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
We have studied 24 cases of secondarily leukemic (stage V) lymphosarcoma (LS), 31 cases of "d'emblee" leukemic LS, and ten cases of lymphoid leukemic neoplasias transitional between "d'emblee" leukemic LS and chronic lymphocytic leukemia (eLL). These cases only concern the common types ofthe WHO classification ofLS, i.e., the prolymphocytic, the lymphoblastic, and the immunoblastic. Some cases have also been classified by cell surface markers. The secondarily leukemic conversion occurred in 40% of the lymphoblastic types, in 14% of the prolymphocytic types, and in 17% of the immunoblastic types. It never occurred at stage I but could occur after any other stage. The mediastinal involvement was observed in three types, but most often in the lymphoblastic type. The prognosis after an acute lymphoid leukemia (ALL) treatment comprising active immunotherapy following chemo(radio)therapy is better for the leukemic prolymphocytic and lymphoblastic LS than for the immunoblastic type. Two patients (one of the lymphoblastic type) are in complete remission after 8 and 5 years, respectively. We have described ten cases of "d'emblee" leukemic LS with either large lymphoid or extra lymphoid masses, bone marrow leukemic cell involvement, and LS aspects of neoplastic cells. Mediastinal, abdominal, or other tumor masses are frequent.
Contents:
I: Clinical Aspects: Staging and Therapeutic Implications.- Introductory Remarks.- Cellular Renewal Kinetics of Malignant Non-Hodgkin's Lymphomas.- Clinical Staging and New Therapeutic Approaches in Multiple Myeloma.- Staging of Myeloma. A Preliminary Study of Staging Factors and Treatment in Different Stages.- Prognostic Factors and Treatment of Multiple Myeloma: Interest of a Cyclic Sequential Chemohormonotherapy Combining Cyclophosphamide, Melphalan, and Prednisone.- Pathological Staging in Adult Previously Untreated Non-Hodgkin's Lymphomas.- Staging in Adult Non-Hodgkin's Lymphomas.- Invasion of the Upper Respiratory and Digestive Tract in Adult Lymphoid Neoplasias.- Non-Hodgkin's Lymphoma of the Upper Digestive and Respiratory Tract: Histopathology and Implications for Treatment.- Staging in Childhood Non-Hodgkin's Lymphoma. What Are Its Benefits? How Extensive Should It Be?.- Systematic Restaging in Non-Hodgkin's Lymphoma: The Need to Define Complete Remission.- Involvement of the Nervous System in Non-Hodgkin's Lymphomas.- Leukemic (or Stage V) Lymphosarcoma.- Comments on "Clinical Aspects: Staging and Therapeutic Implications".- II: Treatment of Non-Hodgkin's Lymphomas.- Radiotherapy of Extranodal Non-Hodgkin's Lymphoma.- Evaluation and Role of Single Chemotherapeutic Agents in Adult Non-Hodgkin's Lymphoma.- General Strategy of Staging and Therapy of Non- Hodgkin's Lymphomas.- Chemotherapy in Non-Hodgkin's Malignant Lymphomas According to Potential Evolutive Groups.- BCG in the Immunotherapy of Non-Hodgkin's Malignant Lymphomas: Preliminary Results of a Controlled Trial.- Chemoimmunotherapy Versus Chemotherapy for Remission Induction in Patients With Non-Hodgkin's Lymphoma: Progress Report of a Southwest Oncology Group Study.- Complications of Total Abdominal and Spleen Irradiation in Patients With Lymphomas.- Effects of Treatment of Malignant Lymphomas on the Granulocytic Progenitor Cells (CFUc).- Preliminary Results of Chemoradiotherapy Followed (or Not) by Active Immunotherapy of Stage III and IV Lymphosarcoma and Reticulosarcoma: Correlation of the Results With WHO Categorization.- Outline of a Prospective Multicentric Study on the Clinical Significance of the Kiel Classification of Non-Hodgkin's Lymphomas.- On the Question of the Tumoricidal Dose in Non-Hodgkin's Lymphomas.- Combined Modality Therapy of Childhood Non-Hodgkin's Lymphoma.- Concluding Remarks on Malignant Lymphomas.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: January, 2012
Pages: 240
Weight: 422g
Availability: Not available (reason unspecified)
Subcategories: General Practice, Oncology
From the same series
Friedhelm Raue
Thomas Ried
Christian Wittekind
Florian Otto
Markus W. Buchler
C. Stroszczynski
Manfred Dietel
H.-J. Senn
Otmar Schober
Jean-Nicolas Vauthey
Elmar Detering
Richard P. Baum
G. Mathe
R. Gross
Florian Otto
Uwe M. Martens
Michail Ignatiadis
Georges Mathe
M. S. Griem
Jack Cuzick
Michael Gnant
Ute Goerling
Hans-Jorg Senn
Werner H. Kirsten
F.A. Langley
Kuan-Teh Jeang
Janusz Jankowski
J. Bernard
Thomas Moehler
Andrea Tannapfel
S.K. Carter
R. S. Nelson
Kerry S. Courneya
Rolf D. Issels
Hans-Jorg Senn
Florian Otto
W. Fischbach
Umberto Veronesi
Otmar Schober
Paul M. Schneider
Hans-Jorg Senn
Wolfgang Tilgen
Jean-Nicolas Vauthey
Richard P. Baum
J. L. Hayward
W. H. Kirsten
Henry T. Lynch
Georges Mathe
G. T. Pack
Leon Goldman
Charles G. Moertel
R.G. Freeman
L. Manuila
Agnes Glaus
Rudiger Liersch
Richard Schindler
Uwe M. Martens
W.A. Fuchs
Michail Ignatiadis
Edward S. Meek
P. Roy-Burman
Merle Mizell
Jean Lindenmann
Pavel Koldovsky
Enrico Anglesio
Georges Mathe
Hans-Jorg Senn
James H. Goldie
Donald Metcalf
Siegfried Seeber
Israel Penn
B. Sokoloff
Manfred Schwab
E. Grundmann
H.-D. Pape
Robert S. Nelson
G. Mathe
J. Lange
G. Bonadonna
J. Szymendera
H. B. Marsden
K. E. Stanley
E. Grundmann
C. Bohuon
Pierre Denoix
A. C. Templeton
Ekkehard Grundmann
Michael Wannenmacher
Ivan Damjanov
Wolf-Dieter Ludwig
Friedhelm Raue
M. L. Jacobs
H.K. Muller-Hermelink
Rita Engenhart-Cabillic
E. Grundmann
Peter M Schlag
E. Grundmann
Ekkehard Grundmann
Donald Metcalf
S. Brunner
F. F. Holmes
G. Mathe
G. Mathe
Pierre Band
Stephen C. Schimpff
K. Schwemmle
Michael Gnant
K. Hoffken
Friedhelm Raue
H. R. Scheurlen
Aron Goldhirsch
H. Acker
Hans-Jorg Senn
F. G. J. Hayhoe
William Duncan
E. Thiel
Hans-Jorg Senn
K. Musshoff
Hans-Jorg Senn
A. Rossi-Fanelli
Peo C. Koller
Volker Diehl
K. Hoffken
H.-J. Senn
Bruce S. Schoenberg
G. St. Arneault
S.K. Carter
B. Henningsen
J. Hekmatpanah
G. Mathe
E. Grundmann
Hans-Jorg Senn
G. Mathe
Sam Brunner
Hans-Jorg Senn
V. Hofmann
Michael Wannenmacher
G. Wagner
Hans-Jorg Senn
Rudolf Pichlmayr
Frank M. Torti
Michael Wannenmacher
William Duncan
G. Mathe
M. Bamberg
H.-P. Lohrmann
E. Grundmann
Niels Neymark
Peter M Schlag
P. Koldovsky
G. Nass
W. Duncan
Ekkehard Grundmann
Richard P. Gallagher
Hans-Jorg Senn
W. Duncan
W. Duncan
S.K. Carter
Michael Molls
Sam Brunner
Peter Boyle
Maurizio Ponz de Leon
U. Reinhold
Gunter Burg
K. Hoffken
H.-J. Senn
F.W. Schildberg
Beat Thurlimann
Janusz Jankowski
Thomas Moehler
Andrea Tannapfel
Kerry S. Courneya
H.-J. Senn
Per-Ulf Tunn
Andreas von Deimling
Antonella Surbone
Ursula Kapp
Hans-Jorg Senn
Santiago Gonzalez-Moreno
Hanno Riess
Paul M. Schneider
Uwe M. Martens
Rudiger Liersch
Renzo Brun del Re
Andreas von Deimling
Ursula Kapp
Per-Ulf Tunn
Hanno Riess
Antonella Surbone
Manfred Dietel
Santiago Gonzalez-Moreno
Louis Denis
H.-J. Senn
C. Stroszczynski