(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
The growth and function of many tissues are influenced by hormones. Therefore it is quite understandable that hormones play a role in the development and treatment of malignant tumors. Numerous publications address this topic; however, the results of many studies are controversial and have not been unequivocally accepted. For nearly 50 years the carcinogenic effect of steroid hormones has been under debate, and their therapeutic value a matter of discussion for equally as long. The present volume concentrates on substantiated data first obtained from the study of tumors developing from hormone regulated or hormone-producing tissue, e.g., the thyroid, adrenal glands, prostate, and the female genital tract. Through a joint approach from the field of molecular biology, biochemistry, and histopathology, advances in the management of these tumors have been elaborated. Another exciting example is the endo nuclear diagnosis of adrenal tumors. Antihormones, i.e. antian drogens or GnRH analogues have proved to be important indeed since they exhibit a destructive effect on prostate carcinomas and breast cancer. Further improvements can be expected in the localization of hormones in tumor tissue by specific antibodies. A special chapter is dedicated to the diffuse endocrine cell system (DECS), the clinical significance of which has mainly become obvious in the gastroenteropancreatic tract.
Contents:
Biological Basics.- Cellular Receptors of Hormones and Nonhormone Ligands in Normal and Malignant Cells.- Localization of Hormones by Antibodies.- Diffuse Endocrine Cell System.- Morphology and Functional Activity of Gastroenteropancreatic Neuroendocrine Tumours.- Clinical Implications of the Diffuse Gastroenteropancreatic Endocrine System.- Thyroid Gland (C-Cell Tumours).- Medullary Carcinoma of the Thyroid.- Growth Regulation of Normal Thyroids and Thyroid Tumors in Man.- Endocrine Aspects of Medullary Thyroid Carcinoma.- Multiple Endocrine Neoplasia Type II.- Adrenal Gland.- Tumours of the Adrenal Gland.- Clinical and Diagnostic Findings in Patients with Chromaffin Tumors: Pheochromocytomas, Pheochromoblastomas.- Adrenocortical Tumors: Clinical and Diagnostic Findings.- Contributions of Nuclear Endocrinology to the Diagnosis of Adrenal Tumors.- Aspects of Surgical Therapy of Adrenal Tumors.- Trends in Endocrine Therapy of Prostate Cancer.- Molecular Biology of the Male Endocrine System.- Development of Hormone Refractory Tumors: Adaption Versus Clonal Selection.- Antiandrogenic Substances in the Management of Prostatic Cancer.- LH-RH Agonist Monotherapy in Patients with Carcinoma of the Prostate and Reflections on the So-called Total Androgen Blockade.- New Developments in Biological Markers in Prostate Cancer.- Aspects of Endocrine-Active and Endocrine-Related Tumors of the Female Genital Tract.- Endocrine and Clinical Aspects of New Compounds for Treatment of Hormone-Related Cancer in Gynecology.- Basic and Clinical Relevance of Hormonal Influence in Breast Cancer.- New Trends in the Endocrine Treatment of Breast Cancer.- Identification of Putative Nonfunctional Steroid Receptors in Breast and Endometrial Cancer.- Hormonal Therapy in Endometrial Carcinoma.- Hormone-Secreting Ovarian Tumors.- Ovarian Hormones and Carcinoma of the Uterine Cervix.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: February, 2012
Pages: 280
Weight: 491g
Availability: Not available (reason unspecified)
Subcategories: Endocrinology, Oncology
From the same series
Friedhelm Raue
Thomas Ried
Christian Wittekind
Florian Otto
Markus W. Buchler
C. Stroszczynski
Manfred Dietel
H.-J. Senn
Otmar Schober
Jean-Nicolas Vauthey
Elmar Detering
Richard P. Baum
G. Mathe
R. Gross
Florian Otto
Uwe M. Martens
Michail Ignatiadis
Georges Mathe
M. S. Griem
Jack Cuzick
Michael Gnant
Ute Goerling
Hans-Jorg Senn
Werner H. Kirsten
F.A. Langley
Kuan-Teh Jeang
Janusz Jankowski
J. Bernard
Thomas Moehler
Andrea Tannapfel
S.K. Carter
R. S. Nelson
Kerry S. Courneya
Rolf D. Issels
Hans-Jorg Senn
Florian Otto
W. Fischbach
Umberto Veronesi
Otmar Schober
Paul M. Schneider
Hans-Jorg Senn
Wolfgang Tilgen
Jean-Nicolas Vauthey
Richard P. Baum
J. L. Hayward
W. H. Kirsten
Henry T. Lynch
Georges Mathe
G. T. Pack
Leon Goldman
Charles G. Moertel
R.G. Freeman
L. Manuila
Agnes Glaus
Rudiger Liersch
Richard Schindler
Uwe M. Martens
W.A. Fuchs
Michail Ignatiadis
Edward S. Meek
P. Roy-Burman
Merle Mizell
Jean Lindenmann
Pavel Koldovsky
Enrico Anglesio
Georges Mathe
Hans-Jorg Senn
James H. Goldie
Donald Metcalf
Siegfried Seeber
Israel Penn
B. Sokoloff
Manfred Schwab
E. Grundmann
H.-D. Pape
Robert S. Nelson
G. Mathe
J. Lange
G. Bonadonna
J. Szymendera
H. B. Marsden
K. E. Stanley
E. Grundmann
C. Bohuon
Pierre Denoix
A. C. Templeton
Michael Wannenmacher
Ivan Damjanov
Wolf-Dieter Ludwig
Friedhelm Raue
M. L. Jacobs
H.K. Muller-Hermelink
Rita Engenhart-Cabillic
E. Grundmann
Peter M Schlag
E. Grundmann
Ekkehard Grundmann
G. Mathe
Donald Metcalf
S. Brunner
F. F. Holmes
G. Mathe
G. Mathe
Pierre Band
Stephen C. Schimpff
K. Schwemmle
Michael Gnant
K. Hoffken
Friedhelm Raue
H. R. Scheurlen
Aron Goldhirsch
H. Acker
Hans-Jorg Senn
F. G. J. Hayhoe
William Duncan
E. Thiel
Hans-Jorg Senn
K. Musshoff
Hans-Jorg Senn
A. Rossi-Fanelli
Peo C. Koller
Volker Diehl
K. Hoffken
H.-J. Senn
Bruce S. Schoenberg
G. St. Arneault
S.K. Carter
B. Henningsen
J. Hekmatpanah
G. Mathe
E. Grundmann
Hans-Jorg Senn
G. Mathe
Sam Brunner
Hans-Jorg Senn
V. Hofmann
Michael Wannenmacher
G. Wagner
Hans-Jorg Senn
Rudolf Pichlmayr
Frank M. Torti
Michael Wannenmacher
William Duncan
G. Mathe
M. Bamberg
H.-P. Lohrmann
E. Grundmann
Niels Neymark
Peter M Schlag
P. Koldovsky
G. Nass
W. Duncan
Ekkehard Grundmann
Richard P. Gallagher
Hans-Jorg Senn
W. Duncan
W. Duncan
S.K. Carter
Michael Molls
Sam Brunner
Peter Boyle
Maurizio Ponz de Leon
U. Reinhold
Gunter Burg
K. Hoffken
H.-J. Senn
F.W. Schildberg
Beat Thurlimann
Janusz Jankowski
Thomas Moehler
Andrea Tannapfel
Kerry S. Courneya
H.-J. Senn
Per-Ulf Tunn
Andreas von Deimling
Antonella Surbone
Ursula Kapp
Hans-Jorg Senn
Santiago Gonzalez-Moreno
Hanno Riess
Paul M. Schneider
Uwe M. Martens
Rudiger Liersch
Renzo Brun del Re
Andreas von Deimling
Ursula Kapp
Per-Ulf Tunn
Hanno Riess
Antonella Surbone
Manfred Dietel
Santiago Gonzalez-Moreno
Louis Denis
H.-J. Senn
C. Stroszczynski