Main description:

The book depicts the various roles of platelets in a variety of cardio-metabolic diseases. Traditional and non-traditional platelet functions are described in detail in atherosclerosis, metabolic syndrome, diabetes, myocardial infarction, and other vascular pathologies. Particular focus is put on platelets as a link between haemostasis and inflammation contributing to both. Last but not least the books links the most recent advances in basic sciences with promising novel therapeutic applications and first results of clinical trials.

The book is written for biomedical scientists in the sub disciplines vascular biology, biochemistry and immunology; and it as well will be of interest and value for academic physicians like cardiologists, hematologists, general internists and vascular surgeons.

Contents:

Cardiac Imaging of Platelets and Inflammation.- Inflammation and Atherosclerosis.- Vaccination to Prevent Cardiovascular Disease.- Platelets as Regulators of Thrombosis and Inflammation.- Diversity of Inflammatory Cells in Vascular Degenerative Disease.- Platelet Inhibition as a Therapeutic Approach in Intravascular Intervention.- Diabetes, Thrombosis, and Cardiovascular Risks.- Therapeutic and Diagnostic Antibody Development.- Diabetes, Inflammation, and Platelets.- Platelet chemokines.- Platelet Signaling.- AMPs and Inflammation.- Platelets and Regeneration.- Platelets HMGB1 and cardiogenic schock.- Platelet cGMP and Vascular motion.- Platelet and Stroke.- Platelets and Polymorphisms.