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Microbicides for Prevention of HIV Infection
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Main description:

One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.


Feature:

Comprehensive overview of the types of microbicides currently in development for HIV/AIDS prevention

Provides a summary of the issues and approaches being taken to address microbicides

Written by leading authorities in the field


Back cover:

One of the most promising new approaches for the prevention of HIV transmission, particularly for developing countries, involves topical, self-administered products known as microbicides. The development of microbicides is a long and complicated process, and this volume provides an overview of all the critical areas, from the selection of appropriate candidate molecules and their formulation, preclinical and clinical testing for safety and efficacy, strategies for product registration and finally, issues associated with product launch, distribution and access. The book will prove valuable to both those working in the field and all others who are interested in learning more about this product class, which has the potential to significantly impact the future of this devastating epidemic.


Contents:

Candidate Microbicides and Their Mechanisms of Action

Carolina Herrera and Robin J. Shattock

 

Microbicide Dosage Forms

L.C. Rohan, B. Devlin and H. Yang

 

Preclinical Safety Evaluation

Jonathon D. S. Holt and Jeremy P. Nuttall

 

Clinical Safety and Pharmacology Trial

Christine Mauck, Andrea Thurman and Jill Schwartz

 

Microbicides for Prevention of HIV Infection: Clinical Efficacy Trials

Salim S. Abdool Karim and Cheryl Baxter

 

Rectal Microbicide Development

Ian McGowan and Charlene Dezzutti

 

Developing Regulatory Strategy for Microbicides

Ronald Nardi, Linda Arterburn, and Lisa Carlton

 

Preparing for Microbicide Introduction, Rollout and Sustained Access

Cynthia Woodsong, Tim Farley and Elizabeth McGrory

 

 


PRODUCT DETAILS

ISBN-13: 9783662445952
Publisher: Springer (Springer Berlin Heidelberg)
Publication date: September, 2014
Pages: 180
Weight: 456g
Availability: POD
Subcategories: Immunology, Microbiology
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CUSTOMER REVIEWS

Average Rating 

“This book offers a detailed review of essentially all aspects of microbicide development, from the basic science underlying microbicide action, to strategic considerations when implementing international microbicide programs. … This text could be used as a primer for researchers entering the burgeoning field of microbicide development or for clinicians who provide these agents.” (Douglas S. Krakower, Clinical Infectious Diseases CID, Vol. 60, June, 2015)