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MORE ABOUT THIS BOOK
Main description:
In Immunotherapy for Infectious Disease, Jeffrey M. Jacobson, MD, and a panel of leading researchers review the state-of-the-art for treating various infections-particularly HIV-by manipulating the immune system's response rather than by chemical drugs. The contributors synthesize the principles of immune defense on the molecular level (monoclonal antibodies, vaccines, methods of antigen presentation, and cytokines and cytokine antagonists), as well as on the cellular and clinical levels levels as a protection against infection. The review of the current state of anti-HIV immunotherapy covers HIV-specific passive and active immunization strategies, gene therapy, and host cell-targeted approaches for treating HIV infection and restoring immune function.
Contents:
Part I. Basic Principles of Immunity
Humoral Immunity
Peter L. Nara
Some Basic Cellular Immunology Principles Applied to the Pathogenesis of Infectious Diseases
R. Pat Bucy and Paul Goepfert
Immune Defense at Mucosal Surfaces
Prosper N. Boyaka and Jerry R. McGhee
Part II. Molecular Basis for Immunotherapy
Production of Immunoglobulins and Monoclonal Antibodies Targeting Infectious Diseases
Renate Kunert and Hermann Katinger
Dendritic Cells: Their Role in the Immune Response to Infectious Organisms and Their Potential Use in Therapeutic Vaccination
Smriti K. Kundu-Raychaudhuri and Edgar G. Engleman
Cytokines, Cytokine Antagonists, and Growth Factors for Treating Infections
Barbara G. Matthews
Principles of Vaccine Development
Constantin A. Bona
Part III. Immunotherapy for HIV Infection
Immunopathogenesis of HIV Infection
Lawrence M. Fox.
Immune Reconstitution with Antiretroviral Chemotherapy
Elizabeth Connick
Active Immunization as Therapy for HIV Infection
Spyros A. Kalams
Passive Immunotherapy for HIV Infection
Jeffrey M. Jacobson
Host Cell-Directed Approaches for Treating HIV and Restoring Immune Function
J. Michael Kilby and R. Pat Bucy
Gene Therapy for HIV-1 Infection
Ralph Dornburg and Roger J. Pomerantz
Part IV. Immunotherapy for Infectious Diseases Other than HIV
Immunotherapy for Viral Infections Other than HIV
Michelle Onorato and Richard B. Pollard
Immunotherapy for Virus-Associated Malignancies
Uluhan Sili, Helen Heslop, and Cliona M. Rooney
Immunotherapy of Bacterial Infections and Sepsis
Sam T. Donta
Immunotherapy for Tuberculosis and Other Mycobacterial Infections
Robert S. Wallis and John L. Johnson
Immunotherapy for Fungal Infections
ArturoCasadevall
Index
PRODUCT DETAILS
Publisher: Springer (Humana Press Inc.)
Publication date: December, 2012
Pages: 344
Weight: 655g
Availability: Available
Subcategories: Immunology, Infectious Diseases
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