Main description:

This book presents state of the art knowledge and practice in the rapidly developing field of bronchiectasis not due to cystic fibrosis. The focus is especially on diagnosis and existing and emerging therapies, but the book also covers a wide range of other key topics, from pathophysiology, histopathology, and immunology through to pulmonary rehabilitation, nursing care, and management in primary care and pediatric settings.

While non-cystic fibrosis bronchiectasis was formerly regarded as an "orphan" disease, international data reveal an increase in its prevalence in recent years. Accordingly, there has been renewed interest in the disease, resulting in more clinical research and the development of new treatments. The impact of bronchiectasis on healthcare systems is substantial and it has a clear attributable mortality. In covering all aspects of the disease, this book will be of interest to respiratory, internal medicine, and infectious disease fellows as well as specialists, final-year medical students, nurses and physiotherapists. The authors are leading experts and chairs of the steering committee of EMBARC, the first truly international bronchiectasis network.

Contents:

Preface.- Introduction.- 1 Radiological diagnosis of bronchiectasis.- 2 Epidemiology and clinical aspects.- 3 Pathophysiology and histopathology of bronchiectasis.- 4 Immunology of bronchiectasis.- 5 How to identify treatable causes and other predisposing factors in bronchiectasis.- 6 Immunodeficit in bronchiectasis.- 7 ENT diseases and bronchiectasis.- 8 Bronchiectasis and ABPA.- 9 COPD and bronchiectasis.- 10 Other predisposing factors for bronchiectasis.- 11 Channelopathies in bronchiectasis.- 12 The severity of the disease and multidisciplinary management.- 13 Pseudomonas aeruginosa in bronchiectasis.- 14 The role of other bacteria, fungi and viruses in bronchiectasis.- 15 NTM in bronchiectasis.- 16 Exacerbation of bronchiectasis.- 17 Long-tern inhaled antibiotic treatment.- 18 Long-term oral antibiotic / anti-inflammatory treatment.- 19 Airway clearance.- 20 Pulmonary rehabilitation.- 21 Nursing management.- 22 Surgery and transplantation in bronchiectasis.- 23 How to manage bronchiectasis in primary care.- 24 An overview of bronchiectasis in children.- Conclusions.