Main description:

This book illustrates the importance and significance of oxidative stress in the pathophysiology of various human diseases.

The book initially introduces the phenomenon of oxidative stress, basic chemical characteristics of the species involved and summarizes the cellular oxidant and anti-oxidant system and the cellular effects and metabolism of the oxidative stress. In addition, it reviews the current understanding of the potential impact of oxidative stress on telomere shortening, aging, and age-related diseases. It also examines the role of oxidative stress in chronic diseases, including cancer, diabetes, cardiovascular diseases, and neurodegenerative disorders.

Further, the book presents novel technologies for the detection of oxidative stress biomarkers using nanostructure biosensors, as well as in vitro and in vivo models to monitor oxidative stress.

Lastly, the book addresses the drug delivery carriers that can help in combating oxidative stress.

Contents:

Chapter 1. Preface.- Chapter 2.Introduction.- Chapter 2.1. Oxidative stress and its biological significance.- Chapter 2.2. Free radicals and biological systems.- Chapter 2.3.Oxidative stress balance system.- Chapter 3. Role of oxidative stress in aging process.- Chapter 4. Oxidative stress in diseases.- Chapter 4.1. Oxidative stress in neurology and in neurodegenerative processes.- Chapter 4.2. Oxidative stress and Cardiology.- Chapter 4.3. Oxidative stress in chronic kidney disease.- Chapter 4.4.Oxidative Stress and Atherosclerosis.- Chapter 4.5. Oxidative stress and cancer.- Chapter 4.6. Oxidative stress in respiratory diseases.- Chapter 4.7. Oxidative stress and epigenetics.- Chapter 5. Oxidative stress monitoring using in vitro and in vivo models.- Chapter 6. Detection of oxidative stress biomarkers using biosensors.- Chapter 7. Pharmaceutical treatments and strategies for anti-oxidative stress.- Chapter 8. Effects of exercise training to the oxidative stress treatment.- Chapter 9. Advancements in novel drug delivery systems: Providing a challenge and threat to oxidative stress in various diseases.- Chapter 10. Future prospects and challenges.- Chapter 11. Bibliography.- Chapter 12. Glossary.