(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
Rhodopsins and Phototransduction Chair: Tôru Yoshizawa 1999 Rhodopsins are.photosensitive proteins with a retinal as the chromophore, and are composed of seven transmembrane helices embedded in the membranes. They function as the photoreceptor proteins for visual transduction and extraocular systems. Upon absorption of light the region–specific isomerization of the retinal chromophore takes place, which is the switching mechanism of the visual transduction process and induces a conformational change of the protein moiety in the rhodopsin molecule. Metarhodopsin II, an intermediate in the bleaching process of rhodopsin, interacts with a G protein and mediates the light signal for further transduction processing in the visual cell. In the past few years, it has been shown that rhodopsin belongs to a large receptor family and that the general mechanism of the signal transduction mediated by this receptor family is almost universal. Fully interdisciplinary, this book brings together protein chemists, molecular biologists, structural biologists, biophysicists, biochemists and photobiologists to discuss their work. Recent data are presented on the photoreceptive mechanism of rhodopsins, the molecular mechanism of the visual transduction process, visual processes in the retina, and other transduction processes in the retina and brain. This book is dedicated to the memory of George Wald.
Back cover:
Rhodopsins and Phototransduction Chair: Tôru Yoshizawa 1999 Rhodopsins are.photosensitive proteins with a retinal as the chromophore, and are composed of seven transmembrane helices embedded in the membranes. They function as the photoreceptor proteins for visual transduction and extraocular systems. Upon absorption of light the region–specific isomerization of the retinal chromophore takes place, which is the switching mechanism of the visual transduction process and induces a conformational change of the protein moiety in the rhodopsin molecule. Metarhodopsin II, an intermediate in the bleaching process of rhodopsin, interacts with a G protein and mediates the light signal for further transduction processing in the visual cell. In the past few years, it has been shown that rhodopsin belongs to a large receptor family and that the general mechanism of the signal transduction mediated by this receptor family is almost universal. Fully interdisciplinary, this book brings together protein chemists, molecular biologists, structural biologists, biophysicists, biochemists and photobiologists to discuss their work. Recent data are presented on the photoreceptive mechanism of rhodopsins, the molecular mechanism of the visual transduction process, visual processes in the retina, and other transduction processes in the retina and brain. This book is dedicated to the memory of George Wald.
Contents:
Professor George Wald Memorial Talk
RUTH HUBBARD and ELIJAH WALD
The ecology of visual pigments
J K BOWMAKER
Evolution of visual pigments and related molecules
FUMIO TOKUNAGA
Structure of rhodopsin obtained by electron cryo–microscopy
GEBHARD F X SCHERTLER
Photons, femtoseconds and dipolar interactions: a molecular picture of the primary events in vision
RICHARD A MATHIES
Photoactivation of rhodopsin: interplay between protein and chromophore
WILLEM J DEGRIP
Colour tuning mechanism of visual pigments
STEVEN W LIN
Amino acid residues controlling properties and functions of rod and cone visual pigments
YOSHINORI SHICHIDA
Signalling states of photoactivated rhodopsin
KLAUS PETER HOFMANN
Molecular mechanism of visual transduction
KRZYSZTOF PALCZEWSKI
Calcium–dependent regulation of rhodopsin phosphorylation
SATORU KAWAMURA
Emerging role of mass spectrometry in molecular biosciences: studies of protein phosphorylation in fly eyes as an example
HIROYUKI MATSUMOTO
Cyclic GMP–gated channel and peripherin/rds–rom–1 complex of rod cells
ROBERT S MOLDAY
Non–visual photoreception by a variety of vertebrate opsins
DAISUKE KOJIMA
PRODUCT DETAILS
Publisher: John Wiley & Sons Ltd (Wiley–Blackwell)
Publication date: September, 2007
Pages: 316
Dimensions: 157.00 x 235.00 x 20.00
Weight: 660g
Availability: Not available (reason unspecified)
Subcategories: Diseases and Disorders
From the same series
CUSTOMER REVIEWS
"This book provides and excellent summary of current work on photopigments and transduction. It should be particularly useful to those vision scientists and other whose primary interests lie elsewhere." (Opthal & Physiolog. Optics , Vol.21, No.5, 2001)