Main description:

Pertussis, or whooping cough, is a respiratory disease caused primarily by infection with the bacterium Bordetella pertussis. It remains among the leading causes of death amongst vaccine-preventable diseases worldwide and recent years have seen its alarming re-emergence in many regions (including the U.S. and much of Europe), despite sustained high levels of vaccine coverage. The causes of the resurgence remain contentious, in part due to inherent complexities of
the pathogen's biology, in part due to pronounced variation in the treatment and prevention strategies between different countries and regions, and in part due to long-standing disagreement amongst scientific researchers studying pertussis. This edited volume brings together expert knowledge from
disparate fields with the overall aim of synthesizing the current understanding of this critically important, global pathogen.

Contents:

1: Pejman Rohani and Samuel V. Scarpino: Introduction to pertussis transmission and epidemiological dynamics
2: Amanda L. Skarlupka, Bodo Linz, Jennifer Maynard, and Eric T. Harvill: Basics of pertussis pathogenesis
3: Mieszko M. Wilk, Aideen C. Allen, Alicja Misiak, Lisa Borkner, and Kingston H.G. Mills: The immunology of Bordetella pertussis infection and vaccination
4: Natasha Crowcroft and Elizabeth Miller: Pertussis epidemiology
5: Jodie McVernon and Hester de Melker: Role of vaccine schedules
6: Eric T. Harvill and Tracy Nicholson: Animal models
7: Francoise Mascart, Violette Dirix, and Camille Locht: The human immune responses to pertussis and pertussis vaccines
8: Sylvain Gandon: Evolutionary epidemiology theory of vaccination
9: Michael R. Weigand, Margaret M. Williams, and Glen Otero: Temporal patterns of Bordetella pertussis genome sequence and structural evolution
10: Ruiting Lan and Sophie Octavia: Vaccine driven selection and the changing molecular epidemiology of Bordetella pertussis
11: Iain MacArthur and Andrew Preston: Congenerics: What can be learned about pertussis from pertussis-like disease caused by other Bordetella?
12: Shelly Bolotin, Helen Quinn, and Peter McIntyre: Surveillance and diagnostics
13: Benjamin M. Althouse and Samuel V. Scarpino: Contrasting ecological and evolutionary signatures of whooping cough epidemiological dynamics
14: Aaron A. King, Matthieu Domenech de Celles, Felicia M. G. Magpantay, and Pejman Rohani: Pertussis immunity and the epidemiological impact of adult transmissiontransmission: Statistical evidence from Sweden and Massachusetts
15: Tami H. Skoff, Colin S. Brown, and Gayatri Amirthalingam: Public health consequences