Main description:

Chesley's Hypertensive Disorders in Pregnancy continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this the hypertensive disorders remain marginally studied and management is often controversial. The fourth edition of Chesley's Hypertensive Disorders in Pregnancy focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, and not just preeclampsia.

Contents:

1. Introduction, History, Controversies, and Definitions
2. The Clinical Spectrum of Preeclampsia
3. Epidemiology of Pregnancy-Related Hypertension
4. Genetic Factors in the Etiology of Preeclampsia
5. The Placenta in Normal Pregnancy and Preeclampsia
6. Angiogenesis and Preeclampsia
7. Metabolic Syndrome and Preeclampsia
8. Immunology of Normal Pregnancy and Preeclampsia
9. Endothelial Cell Dysfunction and Oxidative Stress
10. Animal Models
11. Tests to Predict Preeclampsia
12. Prevention of Preeclampsia and Eclampsia
13. Cerebrovascular (Patho)Physiology in Preeclampsia/ Eclampsia
14. Cardiovascular Alterations in Normal and Preeclamptic Pregnancy
15. The Renin-Angiotensin Systems, their Autoantibodies, and Body Fluid Volume in Preeclampsia
16. The Kidney and Normal Pregnancy and Preeclampsia
17. Platelets, Coagulation, and the Liver
18. Chronic Hypertension and Pregnancy
19. Antihypertensive Treatment
20. Management