Chesley's Hypertensive Disorders in Pregnancy continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this the hypertensive disorders remain marginally studied and management is often controversial. The fourth edition of Chesley's Hypertensive Disorders in Pregnancy focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, and not just preeclampsia.
1. Introduction, History, Controversies, and Definitions2. The Clinical Spectrum of Preeclampsia3. Epidemiology of Pregnancy-Related Hypertension4. Genetic Factors in the Etiology of Preeclampsia5. The Placenta in Normal Pregnancy and Preeclampsia 6. Angiogenesis and Preeclampsia7. Metabolic Syndrome and Preeclampsia8. Immunology of Normal Pregnancy and Preeclampsia 9. Endothelial Cell Dysfunction and Oxidative Stress10. Animal Models11. Tests to Predict Preeclampsia 12. Prevention of Preeclampsia and Eclampsia13. Cerebrovascular (Patho)Physiology in Preeclampsia/ Eclampsia 14. Cardiovascular Alterations in Normal and Preeclamptic Pregnancy15. The Renin-Angiotensin Systems, their Autoantibodies, and Body Fluid Volume in Preeclampsia16. The Kidney and Normal Pregnancy and Preeclampsia 17. Platelets, Coagulation, and the Liver18. Chronic Hypertension and Pregnancy19. Antihypertensive Treatment 20. Management