Main description:

This book discusses normal brain physiology and renal physiology, as well as the interactions between the two. The physiology of the brain can easily be affected by any changes to the physiology of other systems, which in turn may compromise cerebral blood flow and oxygenation. Together the brain and the renal system help our body systems to function automatically.

The book addresses the basic aspects of neurophysiology and renal physiology in three broad sections, the first of which covers the basic principles of cerebral physiology and neural regulation of the renal system. The second part reviews the normal physiology of the renal system, including the mechanism of action, while the last section summarizes the correlation between the brain and kidney. Highly informative and clearly structured, the book provides essential insights for anyone with an interest in physiology and medicine.

Contents:

Section 1: Neurophysiology and Renal system

I. Basics of cerebral physiology

1. Cerebral blood flow and autoregulation

2. Blood cerebrospinal fluid and blood brain barriers

3. Role of brain in body fluid dynamics

II. Neural regulation of renal system

1. Efferent signals from central nervous system to kidneys

a) Neural control of the renal circulation

b) Neural control of renal tubular function

c) Neural control of renal hormonal secretion

2. Afferent signals from kidneys to central nervous system

a) Renorenal reflex control of renal function

b) Mechanisms of activation of renal sensory nerves

3. Role of renal sympathetic nerves in pathophysiological states

a) Hypertension

b) Chronic sodium-retaining edema-forming states

c) Renal inflammation

d) Brain gut kidney axis

4. Approaches towards investigation of the neural regulation of kidney function

Section 2: Normal physiology of Renal System

1. Structure and function of kidney

2. Renal circulation and Glomerular Filtration Rate

3. Transport of solute across kidneys

4. Urine concentration and dilution

5. Physiology of micturition

6. Control of blood volume and composition

7. Regulation of acid-base balance

8. Endocrine function of kidneys

Section 3: Brain - Kidney crosstalk

1. Introduction

2. Brain and Kidney - What is the link?

3. Renal disorders - Definition and Classification

4. Acute kidney Injury in Neurocritically Ill Patients

- Risk factors

- Implication

- Management

5. Contrast- Induced Acute kidney Injury in Neurocritically Ill Patients

- Incidence

- Pathophysiology

- Management

6. Renal replacement therapy in Neurosurgical Patients

- Types

- Complications associated

- Modifications needed in in Neurosurgical Patients

7. Chronic Kidney Disease in Neurosurgical Patients

- Complications

- Alterations in Neuroanesthetic management

8. Neurogenic Systemic Fibrosis