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Molecular Aspects of the Stress Response: Chaperones, Membranes and Networks
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Main description:

This book makes a novel synthesis of the molecular aspects of the stress response and long term adaptation processes with the system biology approach of biological networks. Authored by an exciting mixture of top experts and young rising stars, it provides a comprehensive summary of the field and identifies future trends.


Contents:

Protein Misassembly.- The Cellular "Networking" of Mammalian Hsp27 and Its Functions in the Control of Protein Folding, Redox State and Apoptosis.- Molecular Interaction Network of the Hsp90 Chaperone System.- Organization of the Functions and Components of the Endoplasmic Reticulum.- Molecular Crime and Cellular Punishment.- Chaperones as Parts of Cellular Networks.- Chaperones as Parts of Organelle Networks.- Heat Shock Factor 1 as a Coordinator of Stress and Developmental Pathways.- Chaperone Regulation of the Heat Shock Protein Response.- Mechanisms of Activation and Regulation of the Heat Shock-Sensitive Signaling Pathways.- Membrane-Regulated Stress Response.- Beyond the Lipid Hypothesis.- Trehalose As a "Chemical Chaperone".- Chaperones As Part of Immune Networks.- The Stress of Misfolded Proteins.- Hsp90 and Developmental Networks.


PRODUCT DETAILS

ISBN-13: 9781441922977
Publisher: Springer (Springer-Verlag New York Inc.)
Publication date: November, 2010
Pages: 219
Weight: 426g
Availability: Available
Subcategories: Biochemistry, Immunology
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