Main description:

The International Life Sciences Institute (ILSI) was established in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooper ation in these programs among scientists in universities, industry, and government agencies to assist in the resolu tion of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to har monize toxicologic testing, to advance a more uniform in terpretation of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scien tists. The Monographs on the Pathology of Laboratory Animals are designed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others concerned with evaluating toxicity and carcinogen icity studies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors - strengthens our ex pectations that understanding and cooperation will be im proved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on the eye and ear, is the tenth volume of a set prepared under the sponsorship of the International Life Sciences Institute (ILSI).

Contents:

The Eye.- Cornea.- Anatomy of the Ocular Surfaces, Cornea, and Conjunctiva, Rat and Mouse.- Calcification of the Cornea, Mouse and Rat.- Corneal Opacities, Spontaneous, Mouse.- Lipidosis and Mucopolysaccharidosis of the Cornea Due to Cationic Amphiphilic Drugs, Rat.- Keratoconjunctivitis Sicca and Sequelae, Mouse and Rat.- Uvea (Iris and Ciliary Body).- Cyclitis Produced by Cyclophosphamide, Rat.- Melanoma of the Uvea, Rat.- Melanoma of the Eye, Mouse.- Leiomyoma of the Iris, Sprague-Dawley Rat.- Toxic Effects of 6-Aminonicotinamide, Uvea, Rabbit.- Lens.- Inherited Cataracts, Mouse.- Cataract Due to Tryptophan Deficiency, Rat.- Induced Cataracts, Lens, Rat.- Radiation-Induced Cataracts, Mouse and Rat.- Retina.- Light-Induced Retinal Degeneration, Rat.- Lipidosis of the Retina Due to Cationic Amphiphilic Drugs, Rat.- Inherited Retinal Degeneration, RCS Rat.- Herpesvirus Infection, Experimental, Eye, Mouse.- Lymphocytic Choriomeningitis Virus Infection, Experimental, Eye, Rat.- Cytomegalovirus Infection, Experimental, Eye, Mouse.- Scrapie and Other Experimental Infections, Eye, Mouse.- Retinoblastoma, Experimental, Rat and Hamster.- Toxic Retinopathy, Rat, Mouse, and Hamster.- Eye as a Whole.- Microphthalmia and Anophthalmia, Mouse and Rat.- Lacrimal Glands.- Adenoma and Adenocarcinoma, Harderian Gland, Mouse, Rat, and Hamster.- Atrophy and Sclerosis, Harderian Gland, Rat.- The Ear.- Adenoma of the Auditory Sebaceous Glands, Rat.- Carcinoma of the Auditory Sebaceous Glands, Rat.- Auricular Chondritis, Rat.- Cholesteatoma, Aural, Gerbil.