Main description:

The International Life Sciences Institute (ILSI) was estab lished to stimulate and support scientific research and edu cational programs in nutrition, toxicology, and food safe ty; and to encourage cooperation in these programs among scientists from universities, industry, and government in order to facilitate the resolution of health and safety issues. The officers and trustees of ILSI believe that questions re garding health and safety are best resolved when govern ment and industry rely on scientific investigations, analy ses, and reviews by independent experts. This process is furthered by the examination and discussion of issues on an international basis. ILSI is pleased to sponsor this set of monographs on the pathology of laboratory animals. This project collectively brings together the most comprehensive information on non-neoplastic and neoplastic lesions that occur in com monly used laboratory animals. The international compo sition of the authors, editors, and editorial board who have contributed to these monographs strengthens our expecta tions that understanding and cooperation will be strength ened worldwide through this series.

Contents:

The Genital System.- Embryology and Comparative Anatomy, Rodent Reproductive Tract.- The Ovary.- Normal Structure and Function, Ovary, Hamster.- Neoplasms.- Granulosa/Theca Cell Tumor, Ovary, Rat.- Granulosa Cell Tumor, Ovary, Mouse.- Sertoli's Cell Tumor, Ovary, Rat.- Tubular Adenoma, Ovary, Mouse.- Cystadenoma, Ovary, Mouse.- Teratoma, Ovary, Mouse.- Oviducts/Uterus.- Fetal Development of Male and Female Genital Tract, Mouse.- Neoplasms.- Stromal Sarcoma, Endometrium, Rat.- Deciduosarcomas in Rabbits Induced by a Combination of Estrogen and Progestin.- Papillary Adenoma, Endometrium, Rat.- Adenocarcinoma, Endometrium, Rat.- Squamous Cell Carcinoma, Endometrium/Cervix, Rat.- Lesions of the Female Genital System Caused by Diethylstilbestrol in Humans, Subhuman Primates, and Mice.- Adenoacanthoma, Uterus, Rat.- Leiomyoma and Leiomyosarcoma, Uterus, Rat.- Teratoma, Uterus, Rat.- Yolk Sac Carcinoma, Rat.- Embryonal Carcinoma, Uterus, Rat.- Choriocarcinoma, Uterus, Rat.- Deciduoma, Uterus, Rat.- Stromal Polyp, Endometrium, Rat.- Transplacental Carcinogenesis, Mouse, Rat, Hamster.- Vagina/Vulva.- Structure, Cyclic Change, and Function, Vagina and Vulva, Rat.- Neoplasms.- Adenoma and Adenocarcinoma, Clitoral Gland, Rat.- Testis.- Spermatid Giant Cells, Tubular Hypospermatogenesis, Spermatogonial Swelling, and Cytoplasmic Vacuoles in Testes of Laboratory Rabbits.- Neoplasms.- Interstitial Cell Tumor, Testis, Rat.- Seminoma, Testis, Rat.- Sertoli's Cell Tumor, Testis, Rat.- Nonneoplastic Lesions.- Focal Interstitial Cell Hyperplasia, Testes, Rat.- Testicular Feminization, Testes, and Testicular Tumors, Rat, Mouse.- Testicular Degeneration, Rat.- Atrophy, Testis, Rat.- Ductus Deferens/Epididymis.- Histology and Ultrastructure, Glands of the Ductus Deferens (Ampullary Gland), Rat.- Adenomatous Hyperplasia, Rete Testis, Rat.- Accessory Male Sex Glands.- Anatomy, Histology, and Ultrastructure (Correlation with Function), Prostate, Rat.- Neoplasms.- Adenocarcinoma, Prostate, Rat.- Adenoma, Prostate, Rat.- Hyperplasia, Prostate, Rat.- Adenocarcinoma, Seminal Vesicle/Coagulating Gland, Rat.- Adenoma and Adenocarcinoma, Preputial Gland, Rat.- Granular Cell Tumors of Genital Organs, Mice.- Nonneoplastic Lesions.- Chronic Prostatitis, Rat.