Main description:

This book was developed for the AAPM 2011 Summer School in Burnaby, British Columbia. The focus is on understanding the potential sources of dosimetric uncertainties in radiotherapy; evaluating the impact of these uncertainties on the accuracy and conformity of dose delivered to patients; understanding strategies for mitigating these uncertainties; and understanding the impact of these uncertainties on QA/QM. Summer School Program objectives are to provide in-depth understanding of sources of uncertainties in external beam radiotherapy planning and delivery; practical guidance in assessing the overall uncertainty of delivered dose to patients treated with different technologies; practical guidance on mitigating sources of uncertainties and strategies for dealing with residual uncertainties; and to impress upon the fact that ""What You See Is Not What You Get (WYSINWYG)"" and how to deal with it on patient-by-patient basis.

Contents:

Preface
List of Contributors
Chapter 1 Dosimetric Uncertainties and Normal Tissue Tolerance - Ellen D. Yorke, Ph.D.
Chapter 2 Biologically Conformal Radiotherapy: Targeting Based on Biological Imaging - Robert Jeraj, Stephen Bowen, Michael Deveau,Paulina Galavis, and Ngoneh Jallow
Chapter 3 Immobilization from Rigid to Non-Rigid - Sanford L. Meeks, Ph.D.
Chapter 4 Uncertainties in Reference Dosimetry - Larry A. DeWerd, Ph.D., FAAPM, Tina L. Pike, M.S.,John A. Micka, B.S., and Laura J. Bartol, M.S.
Chapter 5 Treatment Planning Dose Computation - Jeffrey Siebers, Ph.D.
Chapter 6 Uncertainties in the Evaluation of Treatment Plans - Tommy Knoeoes, Ph.D., Hunor Benedek, M.Sc.,Crister Ceberg, Ph.D., Per Nilsson, Ph.D.,and Kristoffer Petersson, M.Sc.
Chapter 7 Motion Management Strategies - Gig S. Mageras, Ph.D., and Peng Peng Zhang, Ph.D.
Chapter 8 Margins and Margin Recipes - Marcel van Herk, Ph.D.
Chapter 9 Robust Optimization - Dualta McQuaid, Jan Unkelbach, Alexei Trofimov, and Thomas Bortfeld
Chapter 10 Limits of Precision and Accuracy of Radiation Delivery Systems - Jean M. Moran, Ph.D., and Timothy Ritter, Ph.D.
Chapter 11 Patient Setup Uncertainties (Interfraction) - Emilie Soisson, Ph.D.
Chapter 12 Developing a Rationale for Tolerance Valuesand Action Levels for the Performance of Planningand Delivery Systems - Jatinder R. Palta, Ph.D., Hosang Jin, Ph.D.,and Siyong Kim, Ph.D.
Chapter 13 Model Planning and Delivery Uncertainties - Siyong Kim, Ph.D., Hosang Jin, Ph.D.,and Jatinder R. Palta, Ph.D.
Chapter 14 Image Guidance To Reduce Setup Error - Lei Dong, Ph.D., and Laurence Court, Ph.D.
Chapter 15 In Vivo Dosimetry for Patients Undergoing External BeamRadiation Therapy - Chester S. Reft, Ph.D.
Chapter 16 Dealing with Intrafraction Motion - Daniel A. Low, Ph.D.
Chapter 17 Uncertainties in Deformable Registration - Kristy K. Brock, Ph.D., Adil Al-Mayah, Ph.D.,and Michael Velec, B.Sc., M.R.T.(T.)
Chapter 18 Uncertainties and Limitations in Adaptive Radiotherapy - Katja M. Langen, Ph.D.
Chapter 19 Challenges of Image-based Response Assessment in Radiation Therapy - James M. Balter, Ph.D.
Chapter 20 Current and Future Quality Practice - Todd A. Pawlicki, Ph.D., and Arno J. Mundt, M.D.
Chapter 21 New Paradigms for Quality Management in Radiation Therapy - M. Saiful Huq, Ph.D.
Chapter 22 Human Performance and the Quality and Safetyof Radiation Therapy - Fang-Fang Yin, Ph.D., Haijun Song, Ph.D.,Jacqueline Maurer, Ph.D., Jennifer O'Daniel, Ph.D.,Eric Klein, Ph.D., and Peter B. Dunscombe, Ph.D.
Chapter 23 Summary of the Reports by the International Commissionon Radiation Units and Measurements on Prescribing,Reporting, and Recording in Radiation Therapy - T. Rock Mackie, Ph.D., and Vincent Gregoire, M.D., Ph.D., Hon F.R.C.R.
Chapter 24 Uncertainties in Selection and Delineation of Target Volumesand Organs at Risk in Head and Neck Tumors - Vincent Gregoire, M.D., Ph.D., Hon. F.R.C.R.
Chapter 25 Thorax - Joe Y. Chang, M.D., Ph.D.
Chapter 26 Assessment and Management of Uncertainties: Overviewof Prostate Cancer Radiotherapy - James Lamb, Ph.D., and Patrick Kupelian, M.D.
Chapter 27 Perspectives on Technology and Practices for AssuringQuality in Radiation Therapy Delivery - D. A. Jaffray, Ph.D., D. Letourneau, Ph.D., and M. K. Islam, Ph.D.