Main description:

TRP channels play a key role in sensory physiology and have been the focus of intensive investigation in recent years. The proposed book will be a comprehensive, detailed overview of the ways in which TRP channels are involved in a wide variety of sensory modalities. Authors will explore the involvement of TRP channels in photo transduction (sight), chemotransduction (taste and odor), mechanotransduction (touch and hearing), thermo transduction (the sensation of temperature) and pain perception. Furthermore, the book will include some grounding chapters such as one on the history of TRP channel research, one on the biophysical characteristics of the proteins and one on trafficking and post-translational regulation.

Contents:

Preface

Rodolfo Madrid, Juan Bacigalupo

Chapter 1. Biophysical and molecular features of thermo sensitive TRP channels involved in sensory transduction

Gonzalo Ferreira, Natalia Raddatz, Yenisleidy Lorenzo, Carlos Gonzalez, Ramon Latorre

Chapter 2. Pharmacology of TRP Channels

Asia Fernandez-Carvajal, Gregorio Fernandez-Ballester, Rosario Gonzalez-Muniz, Antonio Ferrer-Montiel

Chapter 3. Modulation of TRP channels by N-glycosylation and phosphorylation

Maria Pertusa, Rodolfo Madrid

Chapter 4. TRP channels in visual transduction

Juan Bacigalupo, Ricardo Delgado, Yorka Munoz, Peter O'Day

Chapter 5. TRP channels in transduction for responses to odorants and pheromones

Diego Restrepo, Rona Delay, Weihong Lin, Fabian Lopez, Juan Bacigalupo

Chapter 6. TRP channels as targets for modulation of taste transduction

Karel Talavera

Chapter 7. TRP channels and mechanical transduction

Ana Gomis

Chapter 8. TRP channels in the sensation of heat

Chun-Hsiang Tan, Peter A. McNaughton

Chapter 9. TRP channels in cold transduction

Alejandro Gonzalez, Gonzalo Ugarte, Ricardo Pina, Maria Pertusa, Rodolfo Madrid

Chapter 10. Mathematical modeling of TRPM8 and the cold thermoreceptors

Erick Olivares, Patricio Orio