(To see other currencies, click on price)
MORE ABOUT THIS BOOK
Main description:
The importance of the protein kinase family is underscored by numerous disease states that arise due to dysregulation of kinase activity. Recent progress in understanding the molecular regulation of kinases has led to the development of new therapeutics based on the inhibition of kinase activity. In this book, well known experts present their most recent findings on the fast developing kinase field. It will be of interest to basic researchers and the pharmaceutical industry.
Contents:
Proteomics-Based Strategies in Kinase Drug Discovery.- PKC Isotype Functions in T Lymphocytes.- Migration, Cell-Cell Interaction and Adhesion in the Immune System.- Molecular Mechanisms that Control Leukocyte Extravasation Through Endothelial Cell Contacts.- Fragment-Based Drug Discovery Using Rational Design.- Systems Biology of T Cell Activation.- Solving the IRAK-4 Enigma: Application of Kinase-Dead Knock-In Mice.- Sensing, Presenting, and Regulating PAMPS.- The Role of Diacylglycerol Kinases in T Cell Anergy.
PRODUCT DETAILS
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Publication date: April, 2008
Pages: 201
Weight: 477g
Availability: Available
Subcategories: Biochemistry, Immunology, Pharmacology
From the same series
Harald Renz
Alexei Bogdanov
W Wohlleben
P.H. Seeberger
P.A. Schubiger
Bernhard Haendler
Eugene Butcher
Kenneth S. Korach
Shelley L. Berger
H. Graf
John Morser
Heinz-Peter Schultheiss
Andreas Radbruch
S. Bernhard
R. Krattenmacher
Lechoslaw Turski
R.B. Lichtner
H. Graf
Ulrich Dirnagl
I. Schlichting
Kristof Chwalisz
A. Rosenthal
Richard Horuk
Khusru Asadullah
Hinrich Gronemeyer
J. Lindenmann
Eberhard Nieschlag
Robert E. Sobol
U.-F. Habenicht
Markus Schwaiger
R.G.G. Russell
F. Diederich
H. Seidel
Herbert Waldmann
H. Kettenmann
J.A. Dormandy
O. Pelkonen
V. Hansson
Martin Tenniswood
K. Beyreuther
W. Sterry
Peter H. Seeburg
C.N. Serhan
C. Bezold
Jack R. Jr. Lancaster
A. Haverich
Kenneth S. Korach
C. Nüsslein-Volhard
John Eppig
Reinhard Ziegler
E.C. Herrmann
Erwin F. Wagner
A. Cockburn
Peter Ramwell
Orla M. Conneely
Guido Kroemer
Burkhart Schraven
Bernhard Haendler
Manfred T. Reetz
Bernhard Haendler
Guido Kroemer
Stefan Jaroch
Orla M. Conneely
Bernhard Haendler
Andreas Radbruch
P.H. Seeberger
Kenneth S. Korach
B. Weiss
P.A. Schubiger
John Morser
Stefan Jaroch
Shelley L. Berger