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Showing 10 of 94 results for "Series: Ernst Schering Foundation Symposium Proceedings"
 
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Published December, 2014
By Alexei Bogdanov and Kai Licha
Publisher: Springer (Springer-Verlag Berlin and Heidelberg GmbH & Co. K)
Series: Ernst Schering Foundation Symposium Proceedings
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The continuous progress in the understanding of molecular processes of disease formation and progression attributes an increasing importance to biomedical molecular imaging methods.

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€243.99
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Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character.

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Published December, 2014
By W Wohlleben, T Spellig, B Muller-Tiemann, Wolfgang Wohlleben and Beate Muller-Tiemann
Publisher: Springer (Springer Berlin Heidelberg)
Series: Ernst Schering Foundation Symposium Proceedings
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€164.70
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In modern drug discovery and development, chemical synthesis is one of the key technologies. For the rapid preparation of new test compounds and drug development candidates, several innovative technologies with great potential have emerged.

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€153.72
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PET (positron emitting tomography), a nuclear medical imaging modality, is ideally suited to produce three-dimensional images of various targets or processes. The rapidly increasing demand for highly selective probes for MI strongly pushes the development of new PET tracers and PET chemistry.

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Current molecular understanding of estrogen action has greatly profited from advances in molecular cell biology. These advances, and their implications for clinical use, were discussed by leading researchers from industry and academia during an international symposium held in Berlin, 1-3 March 2006 and are featured in this volume.

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Optimal dose individualization has become more important in improving clinical efficacy and safety. Therefore, the role of optimal dose finding in early clinical drug development so as to maximize successful clinical use is emphasized.

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This volume features contributions from participants of an ESRF Workshop on "Systems Biology" held in Berkeley, USA, in November 2005. Recent successes and challenges of applying systems level measurements to the different steps of drug discovery and development in the pharmaceutical industry are summarized.

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€134.19
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Cancer stem cells have originally been identified in leukemia and later in several solid tumor types. Current treatments might largely spare cancer stem cells. This book looks at recent developments in the field of cancer stem cells and the possible impact for the identification of novel treatment paradigms for cancer.

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€195.19
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